beta Amyloid 抗体
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北京 101111
Quick Overview for beta Amyloid 抗体 (ABIN614819)
抗原
See all beta Amyloid (Abeta) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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序列
- DAEFRHDS
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特异性
- This antibody recognizes the N-terminal sequence (DAEFRHDS) of beta Amyloid peptides, and full length beta Amyloid peptide 40, 42 and 43.
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交叉反应 (详细)
- Species reactivity (tested):Human.
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纯化方法
- Affinity Chromatography on Protein G
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免疫原
- Full length Human beta amyloid peptide 43
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亚型
- IgG1
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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溶解方式
- Restore with Double distillated water to adjust the final concentration to 1.0 mg/mL.
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缓冲液
- 0.01 M PBS, pH 7.2
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Store (in aliquots) at -20 °C.
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- beta Amyloid (Abeta) (Amyloid beta (Abeta))
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别名
- Amyloid beta
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背景
- Aβ40, Aβ42 and Aβ43 are different only at the few C-end amino acids. While the C-end amino acids showed no speciesspecificity in mammalians, the Nterminal amino acid sequences have minor discrepancies between difference species. Amyloid beta peptides Aβ42 and Aβ40 have been investigated extensively for predicating Alzheimer's disease. A recent study on A Aβ43 in brain showed that Aβ43 is more fibrillogenic than the other amyloid beta peptides and may be useful as a biomarker or therapeutic target for Alzheimer's disease. Antibody to N-terminal sequence can bind to all the three amyloid beta peptides.
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基因ID
- 351
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途径
- Inflammasome
抗原
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