PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
-20 °C
储存方法
Store at -20°C. Avoid freeze / thaw cycles.
抗原
SMYD5
(SMYD Family Member 5 (SMYD5))
别名
SMYD5
背景
Histone methyltransferase that specifically trimethylates 'Lys-20' of histone H4 to form trimethylated histone H4 lysine 20 (H4K20me3 which represents a specific tag for epigenetic transcriptional repression (By similarity. In association with the NCoR corepressor complex, is involved in the repression of toll-like receptor 4 (TLR4-target inflammatory genes in macrophages by catalyzing the formation of H4K20me3 at the gene promoters (By similarity. Plays an important role in embryonic stem (ES cell self-renewal and differentiation (By similarity. Promotes ES cell maintenance by silencing differentiation genes through deposition of H4K20me3 marks (By similarity. Maintains genome stability of ES cells during differentiation through regulation of heterochromatin formation and repression of endogenous repetitive DNA elements by depositing H4K20me3 marks.,SMYD5,NN8-4AG,RAI15,RRG1,ZMYND23,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,SMYD5