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SIRT6 抗体 (C-Term)

Cited in 1 publication. This anti-SIRT6 antibody is a 兔 多克隆 antibody detecting SIRT6 in WB. Suitable for 小鼠.
产品编号 ABIN6147800
发货至: 中国
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Quick Overview for SIRT6 抗体 (C-Term) (ABIN6147800)

抗原

See all SIRT6 抗体
SIRT6 (Sirtuin 6 (SIRT6))

适用

  • 89
  • 31
  • 18
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  • 1
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小鼠

宿主

  • 85
  • 12
  • 2

克隆类型

  • 79
  • 20
多克隆

标记

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This SIRT6 antibody is un-conjugated

应用范围

  • 78
  • 35
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  • 14
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  • 11
  • 7
  • 7
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Western Blotting (WB)
  • 抗原表位

    • 15
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    • 2
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    C-Term

    序列

    NLQPTKHDRQ ADLRIHGYVD EVMCRLMKHL GLEIPAWDGP CVLDKALPPL PRPVALKAEP PVHLNGAVHV SYKSKPNSPI LHRPPKRVKT EAAPS

    交叉反应

    人, 小鼠

    产品特性

    Polyclonal Antibodies

    免疫原

    A synthetic peptide corresponding to a sequence within amino acids 200 to the C-terminus of mouse SIRT6 (NP_001156902.1).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000

    说明

    HIGH QUALITY

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • Zhu, Yan, Shao, Tian, Zhou: "Downregulation of SIRT6 is associated with poor prognosis in patients with non-small cell lung cancer." in: The Journal of international medical research, Vol. 46, Issue 4, pp. 1517-1527, (2018) (PubMed).

  • 抗原

    SIRT6 (Sirtuin 6 (SIRT6))

    别名

    SIRT6

    背景

    This gene encodes a member of the sirtuin family of NAD-dependent enzymes that are implicated in cellular stress resistance, genomic stability, aging and energy homeostasis. The encoded protein is localized to the nucleus, exhibits ADP-ribosyl transferase and histone deacetylase activities, and plays a role in DNA repair, maintenance of telomeric chromatin, inflammation, lipid and glucose metabolism. Alternative splicing results in multiple transcript variants encoding different isoforms.,SIRT6,SIR2L6,sirtuin 6,Epigenetics & Nuclear Signaling,Chromatin Modifying Enzymes,Deacetylation,SIRT6

    分子量

    36 kDa/39 kDa

    基因ID

    50721

    UniProt

    Q8N6T7
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