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SIGLEC12 抗体 (AA 20-210)

This anti-SIGLEC12 antibody is a 兔 多克隆 antibody detecting SIGLEC12 in WB. Suitable for 人.
产品编号 ABIN6147759
发货至: 中国

Quick Overview for SIGLEC12 抗体 (AA 20-210) (ABIN6147759)

抗原

See all SIGLEC12 抗体
SIGLEC12 (Sialic Acid Binding Ig-Like Lectin 12 (SIGLEC12))

适用

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宿主

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克隆类型

  • 38
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多克隆

标记

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This SIGLEC12 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    AA 20-210

    序列

    EQKDYLLTMQ KSVTVQEGLC VSVLCSFSYP QNGWTASDPV HGYWFRAGDH VSRNIPVATN NPARAVQEET RDRFHLLGDP QNKDCTLSIR DTRESDAGTY VFCVERGNMK WNYKYDQLSV NVTASQDLLS RYRLEVPESV TVQEGLCVSV PCSVLYPHYN WTASSPVYGS WFKEGADIPW DIPVATNTPS G

    交叉反应

    小鼠

    产品特性

    Polyclonal Antibodies

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 20-210 of human SIGLEC12 (NP_443729.1).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000

    说明

    HIGH QUALITY

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    SIGLEC12 (Sialic Acid Binding Ig-Like Lectin 12 (SIGLEC12))

    别名

    SIGLEC12

    背景

    Sialic acid-binding immunoglobulin-like lectins (SIGLECs) are a family of cell surface proteins belonging to the immunoglobulin superfamily. They mediate protein-carbohydrate interactions by selectively binding to different sialic acid moieties present on glycolipids and glycoproteins. This gene encodes a member of the SIGLEC3-like subfamily of SIGLECs. Members of this subfamily are characterized by an extracellular V-set immunoglobulin-like domain followed by two C2-set immunoglobulin-like domains, and the cytoplasmic tyrosine-based motifs ITIM and SLAM-like. The encoded protein, upon tyrosine phosphorylation, has been shown to recruit the Src homology 2 domain-containing protein-tyrosine phosphatases SHP1 and SHP2. It has been suggested that the protein is involved in the negative regulation of macrophage signaling by functioning as an inhibitory receptor. This gene is located in a cluster with other SIGLEC3-like genes on 19q13.4. Alternative splicing results in multiple transcript variants.,SIGLEC12,S2V,SIGLECL1,SLG,Siglec-XII,Immunology & Inflammation,Cell Intrinsic Innate Immunity Signaling Pathway,SIGLEC12

    分子量

    51 kDa/64 kDa

    基因ID

    89858

    UniProt

    Q96PQ1
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