RUNX3 抗体 (AA 210-429)
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北京 101111
Quick Overview for RUNX3 抗体 (AA 210-429) (ABIN6147314)
抗原
See all RUNX3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 210-429
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序列
- DRFGDLERLR MRVTPSTPSP RGSLSTTSHF SSQPQTPIQG TSELNPFSDP RQFDRSFPTL PTLTESRFPD PRMHYPGAMS AAFPYSATPS GTSISSLSVA GMPATSRFHH TYLPPPYPGA PQNQSGPFQA NPSPYHLYYG TSSGSYQFSM VAGSSSGGDR SPTRMLASCT SSAASVAAGN LMNPSLGGQS DGVEADGSHS NSPTALSTPG RMDEAVWRPY
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交叉反应
- 人, 小鼠
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产品特性
- Polyclonal Antibodies
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 210-429 of human RUNX3 (NP_001026850.1).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000,IF,1:50 - 1:100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- RUNX3 (Runt-Related Transcription Factor 3 (RUNX3))
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别名
- RUNX3
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背景
- This gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Alternative splicing results in multiple transcript variants.,RUNX3,AML2,CBFA3,PEBP2aC,Epigenetics & Nuclear Signaling,Transcription Factors,Cell Biology & Developmental Biology,Apoptosis,Target gene,RUNX3
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分子量
- 44 kDa/45 kDa
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基因ID
- 864
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UniProt
- Q13761
抗原
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