Hepcidin 抗体 (AA 25-85)
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Quick Overview for Hepcidin 抗体 (AA 25-85) (ABIN614727)
抗原
See all Hepcidin (HAMP) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 25-85
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特异性
- This antibody reacts to Hepcidin Antimicrobial Peptide (HAMP).
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纯化方法
- Protein A Chromatography
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免疫原
- Recombinant protein, HAMP (AAH20612, 25 a.a. ~ 85 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. Genename: HAMP
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亚型
- IgG1
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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缓冲液
- PBS, pH 7.2
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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- Hepcidin (HAMP) (Hepcidin Antimicrobial Peptide (HAMP))
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别名
- Hepcidin / HAMP
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背景
- Hepcidin, an human antimicrobial peptide, contains a leader sequence, a proteolysis site and a C-terminal 25 amino acid active peptide. This peptide is most active against gram-positive bacteria, but also inhibits the growth of certain yeast and gram-negative bacteria. HAMP also functions as a signaling molecule involved in the maintenance of iron homeostasis. In conjugation with HFE it seems to regulate both intestinal iron absorption and iron storage in macrophages. Mutations in HAMP are found in juvenile hemochromatosis.Synonyms: HEPC, LEAP-1, LEAP1, Liver-expressed antimicrobial peptide, PLTR, Putative liver tumor regressor
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基因ID
- 57817
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NCBI登录号
- NP_066998
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UniProt
- P81172
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途径
- Hormone Activity, Transition Metal Ion Homeostasis
抗原
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