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RPE65 抗体 (AA 274-533)

This anti-RPE65 antibody is a 兔 多克隆 antibody detecting RPE65 in WB 和 IF. Suitable for 人.
产品编号 ABIN6147090
发货至: 中国

Quick Overview for RPE65 抗体 (AA 274-533) (ABIN6147090)

抗原

See all RPE65 抗体
RPE65 (Retinal Pigment Epithelium-Specific Protein 65kDa (RPE65))

适用

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宿主

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克隆类型

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多克隆

标记

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This RPE65 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF)
  • 抗原表位

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    AA 274-533

    序列

    NYMDCFESNE TMGVWLHIAD KKRKKYLNNK YRTSPFNLFH HINTYEDNGF LIVDLCCWKG FEFVYNYLYL ANLRENWEEV KKNARKAPQP EVRRYVLPLN IDKADTGKNL VTLPNTTATA ILCSDETIWL EPEVLFSGPR QAFEFPQINY QKYCGKPYTY AYGLGLNHFV PDRLCKLNVK TKETWVWQEP DSYPSEPIFV SHPDALEEDD GVVLSVVVSP GAGQKPAYLL ILNAKDLSEV ARAEVEINIP VTFHGLFKKS

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 274-533 of human RPE65 (NP_000320.1).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IF,1:50 - 1:200

    说明

    HIGH QUALITY

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    RPE65 (Retinal Pigment Epithelium-Specific Protein 65kDa (RPE65))

    别名

    RPE65

    背景

    This gene encodes a protein which is located in the retinal pigment epithelium and is involved in the production of 11-cis retinal and in visual pigment regeneration. There are two forms of this protein, a soluble form called sRPE65, and a palmitoylated, membrane-bound form known as mRPE65. mRPE65 serves as the palmitoyl donor for lecithin retinol acyl transferase (LRAT), the enzyme that catalyzes the vitamin A to all trans retinol step of the chromophore regeneration process. Both mRPE65 and sRPE65 also serve as regulatory proteins, with the ratio and concentrations of these molecules playing a role in the inhibition of 11-cis retinal synthesis. Mutations in this gene have been associated with Leber congenital amaurosis type 2 (LCA2) and retinitis pigmentosa.,RPE65,BCO3,LCA2,RP20,mRPE65,rd12,sRPE65,Cancer,Signal Transduction,Endocrine & Metabolism,Neuroscience,Cell Type Marker,RPE65

    分子量

    60 kDa

    基因ID

    6121

    UniProt

    Q16518
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