RNF7 抗体 (AA 1-113)
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北京 101111
Quick Overview for RNF7 抗体 (AA 1-113) (ABIN6147047)
抗原
See all RNF7 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-113
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序列
- MADVEDGEET CALASHSGSS GSKSGGDKMF SLKKWNAVAM WSWDVECDTC AICRVQVMDA CLRCQAENKQ EDCVVVWGEC NHSFHNCCMS LWVKQNNRCP LCQQDWVVQR IGK
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交叉反应
- 人
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产品特性
- Polyclonal Antibodies
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-113 of human RNF7 (NP_055060.1).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000,IF,1:20 - 1:50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- RNF7 (Ring Finger Protein 7 (RNF7))
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别名
- RNF7
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背景
- The protein encoded by this gene is a highly conserved ring finger protein. It is an essential subunit of SKP1-cullin/CDC53-F box protein ubiquitin ligases, which are a part of the protein degradation machinery important for cell cycle progression and signal transduction. This protein interacts with, and is a substrate of, casein kinase II (CSNK2A1/CKII). The phosphorylation of this protein by CSNK2A1 has been shown to promote the degradation of IkappaBalpha (CHUK/IKK-alpha/IKBKA) and p27Kip1(CDKN1B). Alternatively spliced transcript variants encoding distinct isoforms have been reported.,RNF7,CKBBP1,ROC2,SAG,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Apoptosis,Cell Cycle,Ubiquitin,Ubiquitin-Proteasome Signaling Pathway,Endocrine & Metabolism,RNF7
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分子量
- 9 kDa/10 kDa/11 kDa/12 kDa
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基因ID
- 9616
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UniProt
- Q9UBF6
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途径
- Positive Regulation of Endopeptidase Activity
抗原
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