RIN1
适用: 大鼠
IF (cc), IF (p)
宿主: 兔
Polyclonal
AbBy Fluor® 680
应用备注
WB,1:500 - 1:2000
限制
仅限研究用
状态
Liquid
缓冲液
PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
-20 °C
储存方法
Store at -20°C. Avoid freeze / thaw cycles.
抗原
RIN1
(Ras and Rab Interactor 1 (RIN1))
别名
RIN1
背景
Ras effector protein, which may serve as an inhibitory modulator of neuronal plasticity in aversive memory formation. Can affect Ras signaling at different levels. First, by competing with RAF1 protein for binding to activated Ras. Second, by enhancing signaling from ABL1 and ABL2, which regulate cytoskeletal remodeling. Third, by activating RAB5A, possibly by functioning as a guanine nucleotide exchange factor (GEF for RAB5A, by exchanging bound GDP for free GTP, and facilitating Ras-activated receptor endocytosis.,RIN1,Epigenetics & Nuclear Signaling,Cancer,Tumor suppressors,Signal Transduction,G protein signaling,Signal Transduction,Neuroscience,RIN1