REST 抗体 (AA 760-1060)
Quick Overview for REST 抗体 (AA 760-1060) (ABIN6146870)
抗原
See all REST 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 760-1060
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序列
- PVKIELSPPI EVVQKEPVQM ELSPPMGVVQ KEPAQREPPP PREPPLHMEP ISKKPPLRKD KKEKSNMQSE RARKEQVLIE VGLVPVKDSW LLKESVSTED LSPPSPPLPK ENLREEASGD QKLLNTGEGN KEAPLQKVGA EEADESLPGL AANINESTHI SSSGQNLNTP EGETLNGKHQ TDSIVCEMKM DTDQNTRENL TGINSTVEEP VSPMLPPSAV EEREAVSKTA LASPPATMAA NESQEIDEDE GIHSHEGSDL SDNMSEGSDD SGLHGARPVP QESSRKNAKE ALAVKAAKGD F
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 760-1060 of human REST/NRSF (NP_001180437.1).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000
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说明
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HIGH QUALITY
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- REST (RE1-Silencing Transcription Factor (REST))
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别名
- REST
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背景
- This gene encodes a transcriptional repressor that represses neuronal genes in non-neuronal tissues. It is a member of the Kruppel-type zinc finger transcription factor family. It represses transcription by binding a DNA sequence element called the neuron-restrictive silencer element. The protein is also found in undifferentiated neuronal progenitor cells and it is thought that this repressor may act as a master negative regular of neurogenesis. Alternatively spliced transcript variants have been described,REST,NRSF,WT6,XBR,Epigenetics & Nuclear Signaling,Transcription Factors,Neuroscience,Neurodegenerative Diseases,REST
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分子量
- 35 kDa/36 kDa/119 kDa/121 kDa
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基因ID
- 5978
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UniProt
- Q13127
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途径
- Negative Regulation of Hormone Secretion, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Chromatin Binding, Positive Regulation of Endopeptidase Activity
抗原
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