RCC1 抗体 (AA 1-240)
Quick Overview for RCC1 抗体 (AA 1-240) (ABIN6146817)
抗原
See all RCC1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-240
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序列
- MSPKRIAKRR SPPADAIPKS KKVKVSHRSH STEPGLVLTL GQGDVGQLGL GENVMERKKP ALVSIPEDVV QAEAGGMHTV CLSKSGQVYS FGCNDEGALG RDTSVEGSEM VPGKVELQEK VVQVSAGDSH TAALTDDGRV FLWGSFRDNN GVIGLLEPMK KSMVPVQVQL DVPVVKVASG NDHLVMLTAD GDLYTLGCGE QGQLGRVPEL FANRGGRQGL ERLLVPKCVM LKSRGSRGHV
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human RCC1 (NP_001260.1).
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亚型
- IgG
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应用备注
- WB,1:1000 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
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说明
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HIGH QUALITY
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- RCC1 (Regulator of Chromosome Condensation 1 (RCC1))
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别名
- RCC1
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背景
- Guanine-nucleotide releasing factor that promotes the exchange of Ran-bound GDP by GTP, and thereby plays an important role in RAN-mediated functions in nuclear import and mitosis. Contributes to the generation of high levels of chromosome-associated, GTP-bound RAN, which is important for mitotic spindle assembly and normal progress through mitosis. Via its role in maintaining high levels of GTP-bound RAN in the nucleus, contributes to the release of cargo proteins from importins after nuclear import. Involved in the regulation of onset of chromosome condensation in the S phase. Binds both to the nucleosomes and double-stranded DNA.,RCC1,CHC1,RCC1-I,SNHG3-RCC1,Cell Biology & Developmental Biology,Cell Cycle,RCC1
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分子量
- 44 kDa/48 kDa
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基因ID
- 1104
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UniProt
- P18754
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途径
- Chromatin Binding, Protein targeting to Nucleus
抗原
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