RASGRP1 抗体 (AA 598-797)
Quick Overview for RASGRP1 抗体 (AA 598-797) (ABIN6146720)
抗原
See all RASGRP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 598-797
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序列
- PVAPTENNTS VGPVSNLCSL GAKDLLHAPE EGPFTFPNGE AVEHGEESKD RTIMLMGVSS QKISLRLKRA VAHKATQTES QPWIGSEGPS GPFVLSSPRK TAQDTLYVLP SPTSPCPSPV LVRKRAFVKW ENKDSLIKSK EELRHLRLPT YQELEQEINT LKADNDALKI QLKYAQKKIE SLQLEKSNHV LAQMEQGDCS
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 598-797 of human RASGRP1 (NP_005730.2).
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亚型
- IgG
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anti-RAS Guanyl Releasing Protein 1 (Calcium and DAG-Regulated) (RASGRP1) (AA 495-521) antibody
RASGRP1 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB21940 unconjugated
anti-RAS Guanyl Releasing Protein 1 (Calcium and DAG-Regulated) (RASGRP1) (AA 594-716) antibodyRASGRP1 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-RAS Guanyl Releasing Protein 1 (Calcium and DAG-Regulated) (RASGRP1) (AA 617-666) antibodyRASGRP1 适用: 人, 豚鼠, 小鼠, 兔 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB,1:1000 - 1:2000,IF,1:50 - 1:200
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说明
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HIGH QUALITY
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- RASGRP1 (RAS Guanyl Releasing Protein 1 (Calcium and DAG-Regulated) (RASGRP1))
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别名
- RASGRP1
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背景
- This gene is a member of a family of genes characterized by the presence of a Ras superfamily guanine nucleotide exchange factor (GEF) domain. It functions as a diacylglycerol (DAG)-regulated nucleotide exchange factor specifically activating Ras through the exchange of bound GDP for GTP. It activates the Erk/MAP kinase cascade and regulates T-cells and B-cells development, homeostasis and differentiation. Alternatively spliced transcript variants encoding different isoforms have been identified. Altered expression of the different isoforms of this protein may be a cause of susceptibility to systemic lupus erythematosus (SLE).,RASGRP1,CALDAG-GEFI,CALDAG-GEFII,RASGRP,V,hRasGRP1,Cancer,Signal Transduction,G protein signaling,Signal Transduction,Immunology & Inflammation,B Cell Receptor Signaling Pathway,T Cell Receptor Signaling Pathway,Neuroscience,Calcium Signaling,RASGRP1
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分子量
- 55 kDa/62 kDa/68 kDa/86 kDa/90 kDa
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基因ID
- 10125
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UniProt
- O95267
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途径
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway
抗原
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