RAMP1 抗体 (AA 27-117)
Quick Overview for RAMP1 抗体 (AA 27-117) (ABIN6146672)
抗原
See all RAMP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 27-117
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序列
- CQEANYGALL RELCLTQFQV DMEAVGETLW CDWGRTIRSY RELADCTWHM AEKLGCFWPN AEVDRFFLAV HGRYFRSCPI SGRAVRDPPG S
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 27-117 of human RAMP1 (NP_005846.1).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000,IF,1:50 - 1:200
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说明
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HIGH QUALITY
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- RAMP1 (Receptor (G Protein-Coupled) Activity Modifying Protein 1 (RAMP1))
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别名
- RAMP1
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背景
- The protein encoded by this gene is a member of the RAMP family of single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. RAMPs are required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane. CRLR, a receptor with seven transmembrane domains, can function as either a calcitonin-gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed. In the presence of this (RAMP1) protein, CRLR functions as a CGRP receptor. The RAMP1 protein is involved in the terminal glycosylation, maturation, and presentation of the CGRP receptor to the cell surface. Alternative splicing results in multiple transcript variants encoding different isoforms.,RAMP1,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),Neuroscience,RAMP1
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分子量
- 16 kDa
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基因ID
- 10267
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UniProt
- O60894
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途径
- cAMP Metabolic Process, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of Carbohydrate Metabolic Process
抗原
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