PYGL 抗体 (AA 1-280)
Quick Overview for PYGL 抗体 (AA 1-280) (ABIN6146525)
抗原
See all PYGL 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-280
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序列
- MAKPLTDQEK RRQISIRGIV GVENVAELKK SFNRHLHFTL VKDRNVATTR DYYFALAHTV RDHLVGRWIR TQQHYYDKCP KRVYYLSLEF YMGRTLQNTM INLGLQNACD EAIYQLGLDI EELEEIEEDA GLGNGGLGRL AACFLDSMAT LGLAAYGYGI RYEYGIFNQK IRDGWQVEEA DDWLRYGNPW EKSRPEFMLP VHFYGKVEHT NTGTKWIDTQ VVLALPYDTP VPGYMNNTVN TMRLWSARAP NDFNLRDFNV GDYIQAVLDR NLAENISRVL
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human PYGL (NP_002854.3).
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亚型
- IgG
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anti-phosphorylase, Glycogen, Liver (PYGL) (AA 370-538) antibody
PYGL 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-phosphorylase, Glycogen, Liver (PYGL) (AA 2-846) antibodyPYGL 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-phosphorylase, Glycogen, Liver (PYGL) antibodyPYGL 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-phosphorylase, Glycogen, Liver (PYGL) (AA 1-847) antibodyPYGL 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-phosphorylase, Glycogen, Liver (PYGL) (AA 341-509) antibodyPYGL 适用: 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-phosphorylase, Glycogen, Liver (PYGL) (AA 809-843) antibodyPYGL 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB53470 unconjugated
anti-phosphorylase, Glycogen, Liver (PYGL) (C-Term) antibodyPYGL 适用: 人, 猴 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-phosphorylase, Glycogen, Liver (PYGL) (Internal Region) antibodyPYGL 适用: 人, 犬 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-phosphorylase, Glycogen, Liver (PYGL) (AA 603-750) antibodyPYGL 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-phosphorylase, Glycogen, Liver (PYGL) (AA 73-267) antibodyPYGL 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200,IP,1:50 - 1:200
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说明
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HIGH QUALITY
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- PYGL (phosphorylase, Glycogen, Liver (PYGL))
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别名
- PYGL
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背景
- This gene encodes a homodimeric protein that catalyses the cleavage of alpha-1,4-glucosidic bonds to release glucose-1-phosphate from liver glycogen stores. This protein switches from inactive phosphorylase B to active phosphorylase A by phosphorylation of serine residue 15. Activity of this enzyme is further regulated by multiple allosteric effectors and hormonal controls. Humans have three glycogen phosphorylase genes that encode distinct isozymes that are primarily expressed in liver, brain and muscle, respectively. The liver isozyme serves the glycemic demands of the body in general while the brain and muscle isozymes supply just those tissues. In glycogen storage disease type VI, also known as Hers disease, mutations in liver glycogen phosphorylase inhibit the conversion of glycogen to glucose and results in moderate hypoglycemia, mild ketosis, growth retardation and hepatomegaly. Alternative splicing results in multiple transcript variants encoding different isoforms.,PYGL,GSD6,Cancer,Signal Transduction,Endocrine & Metabolism,Carbohydrate metabolism,PYGL
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分子量
- 93 kDa/97 kDa
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基因ID
- 5836
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UniProt
- P06737
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途径
- Carbohydrate Homeostasis, Cellular Glucan Metabolic Process
抗原
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