PRDM6 抗体 (AA 376-595)
This anti-PRDM6 antibody is a 兔 多克隆 antibody detecting PRDM6 in WB. Suitable for 人.
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Quick Overview for PRDM6 抗体 (AA 376-595) (ABIN6146147)
抗原
See all PRDM6 抗体
PRDM6
(PR Domain Containing 6 (PRDM6))
适用
人
宿主
兔
克隆类型
多克隆
标记
This PRDM6 antibody is un-conjugated
应用范围
Western Blotting (WB)
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抗原表位
- AA 376-595
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序列
- LQCIAQDENL NVPSTVMEAM CRQDALQPFN KSSKLAPTTQ QRSVVFPQTP CSRNFSLLDK SGPIESGFNQ INVKNQRVLA SPTSTSQLHS EFSDWHLWKC GQCFKTFTQR ILLQMHVCTQ NPDRPYQCGH CSQSFSQPSE LRNHVVTHSS DRPFKCGYCG RAFAGATTLN NHIRTHTGEK PFKCERCERS FTQATQLSRH QRMPNECKPI TESPESIEVD
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 376-595 of human PRDM6 (NP_001129711.1).
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亚型
- IgG
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anti-PR Domain Containing 6 (PRDM6) (AA 448-477) antibody
PRDM6 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-PR Domain Containing 6 (PRDM6) (N-Term) antibodyPRDM6 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB,1:500 - 1:2000
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说明
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HIGH QUALITY
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- PRDM6 (PR Domain Containing 6 (PRDM6))
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别名
- PRDM6
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背景
- Putative histone methyltransferase that acts as a transcriptional repressor of smooth muscle gene expression. Promotes the transition from differentiated to proliferative smooth muscle by suppressing differentiation and maintaining the proliferative potential of vascular smooth muscle cells. Also plays a role in endothelial cells by inhibiting endothelial cell proliferation, survival and differentiation. It is unclear whether it has histone methyltransferase activity in vivo. According to some authors, it does not act as a histone methyltransferase by itself and represses transcription by recruiting EHMT2/G9a. According to others, it possesses histone methyltransferase activity when associated with other proteins and specifically methylates 'Lys-20' of histone H4 in vitro. 'Lys-20' methylation represents a specific tag for epigenetic transcriptional repression.,PRDM6,KMT8C,PDA3,PRISM,Epigenetics & Nuclear Signaling,PRDM6
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分子量
- 14 kDa/46 kDa/64 kDa
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基因ID
- 93166
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UniProt
- Q9NQX0
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途径
- Regulation of Muscle Cell Differentiation
抗原
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