PLOD1 抗体 (AA 488-727)
Quick Overview for PLOD1 抗体 (AA 488-727) (ABIN6145784)
抗原
See all PLOD1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 488-727
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序列
- RQQDVFMFLT NRHTLGHLLS LDSYRTTHLH NDLWEVFSNP EDWKEKYIHQ NYTKALAGKL VETPCPDVYW FPIFTEVACD ELVEEMEHFG QWSLGNNKDN RIQGGYENVP TIDIHMNQIG FEREWHKFLL EYIAPMTEKL YPGYYTRAQF DLAFVVRYKP DEQPSLMPHH DASTFTINIA LNRVGVDYEG GGCRFLRYNC SIRAPRKGWT LMHPGRLTHY HEGLPTTRGT RYIAVSFVDP
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 488-727 of human PLOD1 (NP_000293.2).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000
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说明
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HIGH QUALITY
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- PLOD1 (Procollagen-Lysine,2-Oxoglutarate 5-Dioxygenase 1 (PLOD1))
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别名
- PLOD1
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背景
- Lysyl hydroxylase is a membrane-bound homodimeric protein localized to the cisternae of the endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VI have deficiencies in lysyl hydroxylase activity. Two transcript variants encoding different isoforms have been found for this gene.,PLOD1,EDS6,LH,LH1,LLH,PLOD,Epigenetics & Nuclear Signaling,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Extracellular Matrix,Collagen,PLOD1
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分子量
- 83 kDa/88 kDa
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基因ID
- 5351
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UniProt
- Q02809
抗原
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