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PIAS3 抗体 (AA 452-628)

This anti-PIAS3 antibody is a 兔 多克隆 antibody detecting PIAS3 in WB 和 IHC. Suitable for 人.
产品编号 ABIN6145599
发货至: 中国

Quick Overview for PIAS3 抗体 (AA 452-628) (ABIN6145599)

抗原

See all PIAS3 抗体
PIAS3 (Protein Inhibitor of Activated STAT, 3 (PIAS3))

适用

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宿主

  • 32
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克隆类型

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多克隆

标记

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This PIAS3 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    AA 452-628

    序列

    IESSSDEEDL PPTKKHCSVT SAAIPALPGS KGVLTSGHQP SSVLRSPAMG TLGGDFLSSL PLHEYPPAFP LGADIQGLDL FSFLQTESQH YGPSVITSLD EQDALGHFFQ YRGTPSHFLG PLAPTLGSSH CSATPAPPPG RVSSIVAPGG ALREGHGGPL PSGPSLTGCR SDIISLD

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 452-628 of human PIAS3 (NP_006090.2).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IHC,1:50 - 1:100

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    PIAS3 (Protein Inhibitor of Activated STAT, 3 (PIAS3))

    别名

    PIAS3

    背景

    This gene encodes a member of the PIAS [protein inhibitor of activated STAT (signal transducer and activator of transcription)] family of transcriptional modulators. The protein functions as a SUMO (small ubiquitin-like modifier)-E3 ligase which catalyzes the covalent attachment of a SUMO protein to specific target substrates. It directly binds to several transcription factors and either blocks or enhances their activity. Alternatively spliced transcript variants of this gene have been identified, but the full-length nature of some of these variants has not been determined.,PIAS3,ZMIZ5,Epigenetics & Nuclear Signaling,Transcription Factors,Cell Biology & Developmental Biology,Ubiquitin,Ubiquitin-Proteasome Signaling Pathway,Immunology & Inflammation,IL-6 Receptor Signaling Pathway,PIAS3

    分子量

    68 kDa

    基因ID

    10401

    UniProt

    Q9Y6X2

    途径

    JAK/STAT Signaling
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