PHF19 抗体 (AA 1-207)
This anti-PHF19 antibody is a 兔 多克隆 antibody detecting PHF19 in WB 和 IF. Suitable for 人.
Quick Overview for PHF19 抗体 (AA 1-207) (ABIN6145539)
抗原
See all PHF19 抗体
PHF19
(PHD Finger Protein 19 (PHF19))
适用
人
宿主
兔
克隆类型
多克隆
标记
This PHF19 antibody is un-conjugated
应用范围
Western Blotting (WB), Immunofluorescence (IF)
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抗原表位
- AA 1-207
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序列
- MENRALDPGT RDSYGATSHL PNKGALAKVK NNFKDLMSKL TEGQYVLCRW TDGLYYLGKI KRVSSSKQSC LVTFEDNSKY WVLWKDIQHA GVPGEEPKCN ICLGKTSGPL NEILICGKCG LGYHQQCHIP IAGSADQPLL TPWFCRRCIF ALAVRVSLPS SPVPASPASS SGADQRLPSQ SLSSKQKGHT WALETDSASA TVLGQDL
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-207 of human PHF19 (NP_001009936.1).
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亚型
- IgG
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anti-PHD Finger Protein 19 (PHF19) (AA 1-207) antibody
PHF19 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-PHD Finger Protein 19 (PHF19) (C-Term) antibodyPHF19 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB,1:500 - 1:2000,IF,1:50 - 1:100
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说明
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HIGH QUALITY
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- PHF19 (PHD Finger Protein 19 (PHF19))
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别名
- PHF19
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背景
- Polycomb group (PcG protein that specifically binds histone H3 trimethylated at 'Lys-36' (H3K36me3 and recruits the PRC2 complex, thus enhancing PRC2 H3K27me3 methylation activity. Probably involved in the transition from an active state to a repressed state in embryonic stem cells: acts by binding to H3K36me3, a mark for transcriptional activation, and recruiting H3K36me3 histone demethylases RIOX1 or KDM2B, leading to demethylation of H3K36 and recruitment of the PRC2 complex that mediates H3K27me3 methylation, followed by de novo silencing. Recruits the PRC2 complex to CpG islands and contributes to embryonic stem cell self-renewal. Also binds histone H3 dimethylated at 'Lys-36' (H3K36me2. Isoform 1 and isoform 2 inhibit transcription from an HSV-tk promoter.,PHF19,MTF2L1,PCL3,TDRD19B,Epigenetics & Nuclear Signaling,Transcription Factors,PHF19
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分子量
- 14 kDa/22 kDa/65 kDa
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基因ID
- 26147
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UniProt
- Q5T6S3
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途径
- Stem Cell Maintenance
抗原
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