PDE6B 抗体 (AA 1-190)
Quick Overview for PDE6B 抗体 (AA 1-190) (ABIN6145363)
抗原
See all PDE6B 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-190
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序列
- MSLSEEQARS FLDQNPDFAR QYFGKKLSPE NVAAACEDGC PPDCDSLRDL CQVEESTALL ELVQDMQESI NMERVVFKVL RRLCTLLQAD RCSLFMYRQR NGVAELATRL FSVQPDSVLE DCLVPPDSEI VFPLDIGVVG HVAQTKKMVN VEDVAECPHF SSFADELTDY KTKNMLATPI MNGKDVVAVI
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-190 of human PDE6B (NP_001138763.1).
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亚型
- IgG
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anti-phosphodiesterase 6B, CGMP-Specific, Rod, beta (PDE6B) antibody
PDE6B 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-phosphodiesterase 6B, CGMP-Specific, Rod, beta (PDE6B) (AA 1-853) antibodyPDE6B 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-phosphodiesterase 6B, CGMP-Specific, Rod, beta (PDE6B) (AA 105-154) antibodyPDE6B 适用: 人, Cow, 犬, 马, 豚鼠, 兔, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-phosphodiesterase 6B, CGMP-Specific, Rod, beta (PDE6B) (AA 372-421) antibodyPDE6B 适用: 人, Cow, 犬, 马 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:50 - 1:100
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说明
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HIGH QUALITY
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- PDE6B (phosphodiesterase 6B, CGMP-Specific, Rod, beta (PDE6B))
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别名
- PDE6B
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背景
- Photon absorption triggers a signaling cascade in rod photoreceptors that activates cGMP phosphodiesterase (PDE), resulting in the rapid hydrolysis of cGMP, closure of cGMP-gated cation channels, and hyperpolarization of the cell. PDE is a peripheral membrane heterotrimeric enzyme made up of alpha, beta, and gamma subunits. This gene encodes the beta subunit. Mutations in this gene result in retinitis pigmentosa and autosomal dominant congenital stationary night blindness. Multiple transcript variants encoding different isoforms have been found for this gene.,PDE6B,CSNB3,CSNBAD2,PDEB,RP40,rd1,GMP-PDEbeta,Signal Transduction,Neuroscience,PDE6B
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分子量
- 66 kDa/98 kDa
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基因ID
- 5158
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UniProt
- P35913
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途径
- Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction
抗原
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