PCDHA12 抗体 (AA 713-792)
Quick Overview for PCDHA12 抗体 (AA 713-792) (ABIN6145297)
抗原
See all PCDHA12 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 713-792
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序列
- LTLLLYTALR CSAPPTVSRC APGKPTLVCS SAVGSWSYSQ QRRQRVCSAE SPPKTDLMAF SPSLQLSRED CLNPPSEVSY
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 713-792 of human PCDHA12 (NP_114070.1).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000
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说明
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HIGH QUALITY
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- PCDHA12 (Protocadherin alpha 12 (PCDHA12))
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别名
- PCDHA12
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背景
- This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined.,PCDHA12,PCDH-ALPHA12,Cancer,Invasion and Metastasis,Signal Transduction,Cell Biology & Developmental Biology,Cell Cycle,Centrosome,Cell Adhesion,Cadherins,Cytoskeleton,Neuroscience,Calcium Signaling,PCDHA12
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分子量
- 85 kDa/101 kDa
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基因ID
- 56137
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UniProt
- Q9UN75
抗原
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