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PAX5 抗体 (AA 1-100)

This anti-PAX5 antibody is a 兔 多克隆 antibody detecting PAX5 in WB. Suitable for 人.
产品编号 ABIN6145258
发货至: 中国

Quick Overview for PAX5 抗体 (AA 1-100) (ABIN6145258)

抗原

See all PAX5 抗体
PAX5 (Paired Box 5 (PAX5))

适用

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宿主

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  • 5
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克隆类型

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  • 34
多克隆

标记

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This PAX5 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    AA 1-100

    序列

    MDLEKNYPTP RTSRTGHGGV NQLGGVFVNG RPLPDVVRQR IVELAHQGVR PCDISRQLRV SHGCVSKILG RYYETGSIKP GVIGGSKPKV ATPKVVEKIA

    交叉反应

    人, 大鼠

    产品特性

    Polyclonal Antibodies

    免疫原

    A synthetic peptide corresponding to a sequence within amino acids 1-100 of human PAX5 (NP_057953.1).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000

    说明

    HIGH QUALITY

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    PAX5 (Paired Box 5 (PAX5))

    别名

    PAX5

    背景

    This gene encodes a member of the paired box (PAX) family of transcription factors. The central feature of this gene family is a novel, highly conserved DNA-binding motif, known as the paired box. Paired box transcription factors are important regulators in early development, and alterations in the expression of their genes are thought to contribute to neoplastic transformation. This gene encodes the B-cell lineage specific activator protein that is expressed at early, but not late stages of B-cell differentiation. Its expression has also been detected in developing CNS and testis and so the encoded protein may also play a role in neural development and spermatogenesis. This gene is located at 9p13, which is involved in t(9,14)(p13,q32) translocations recurring in small lymphocytic lymphomas of the plasmacytoid subtype, and in derived large-cell lymphomas. This translocation brings the potent E-mu enhancer of the IgH gene into close proximity of the PAX5 promoter, suggesting that the deregulation of transcription of this gene contributes to the pathogenesis of these lymphomas. Alternative splicing results in multiple transcript variants encoding different isoforms.,PAX5,ALL3,BSAP,Epigenetics & Nuclear Signaling,Transcription Factors,Neuroscience,PAX5

    分子量

    31 kDa/32 kDa/34 kDa/35 kDa/37 kDa/38 kDa/42 kDa

    基因ID

    5079

    UniProt

    Q02548
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