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OTX2 抗体 (AA 140-280)

This anti-OTX2 antibody is a 兔 多克隆 antibody detecting OTX2 in IHC 和 IF. Suitable for 人.
产品编号 ABIN6145090
发货至: 中国

Quick Overview for OTX2 抗体 (AA 140-280) (ABIN6145090)

抗原

See all OTX2 抗体
OTX2 (Orthodenticle Homeobox 2 (OTX2))

适用

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宿主

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克隆类型

  • 51
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多克隆

标记

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This OTX2 antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 抗原表位

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    AA 140-280

    序列

    TPPSSTSVPT IASSSAPVSI WSPASISPLS DPLSTSSSCM QRSYPMTYTQ ASGYSQGYAG STSYFGGMDC GSYLTPMHHQ LPGPGATLSP MGTNAVTSHL NQSPASLSTQ GYGASSLGFN STTDCLDYKD QTASWKLNFN A

    交叉反应

    小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 140-280 of human OTX2 (NP_068374.1).

    亚型

    IgG
  • 应用备注

    IHC,1:50 - 1:100,IF,1:50 - 1:100

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    OTX2 (Orthodenticle Homeobox 2 (OTX2))

    别名

    OTX2

    背景

    This gene encodes a member of the bicoid subfamily of homeodomain-containing transcription factors. The encoded protein acts as a transcription factor and plays a role in brain, craniofacial, and sensory organ development. The encoded protein also influences the proliferation and differentiation of dopaminergic neuronal progenitor cells during mitosis. Mutations in this gene cause syndromic microphthalmia 5 (MCOPS5) and combined pituitary hormone deficiency 6 (CPHD6). This gene is also suspected of having an oncogenic role in medulloblastoma. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Pseudogenes of this gene are known to exist on chromosomes two and nine.,OTX2,CPHD6,MCOPS5,Epigenetics & Nuclear Signaling,Transcription Factors,Cell Biology & Developmental Biology,Neuroscience,Stem Cells,OTX2

    分子量

    31 kDa/32 kDa

    基因ID

    5015

    UniProt

    P32243

    途径

    Dopaminergic Neurogenesis
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