NPRL2 抗体 (AA 1-220)
Quick Overview for NPRL2 抗体 (AA 1-220) (ABIN6144787)
抗原
See all NPRL2 抗体适用
宿主
克隆类型
标记
应用范围
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    - 
                                            抗原表位
- AA 1-220
- 
                                            序列
- MGSGCRIECI FFSEFHPTLG PKITYQVPED FISRELFDTV QVYIITKPEL QNKLITVTAM EKKLIGCPVC IEHKKYSRNA LLFNLGFVCD AQAKTCALEP IVKKLAGYLT TLELESSFVS MEESKQKLVP IMTILLEELN ASGRCTLPID ESNTIHLKVI EQRPDPPVAQ EYDVPVFTKD KEDFFNSQWD LTTQQILPYI DGFRHIQKIS AEADVELNLV
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                                            交叉反应
- 人, 小鼠, 大鼠
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                                            产品特性
- Polyclonal Antibodies
- 
                                            免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human NPRL2 (NP_006536.3).
- 
                                            亚型
- IgG
 
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    - 
                                            应用备注
- WB,1:500 - 1:2000,IF,1:50 - 1:200
- 
                                            说明
- 
                        HIGH QUALITY 
- 
                                            限制
- 仅限研究用
 
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- 
    - 
                                            状态
- Liquid
- 
                                            缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- 
                                            储存液
- Sodium azide
- 
                                            注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 
                                            储存条件
- -20 °C
- 
                                            储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
 
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    - NPRL2 (Nitrogen Permease Regulator-Like 2 (S. Cerevisiae) (NPRL2))
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                                            别名
- NPRL2
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                                            背景
- As a component of the GATOR1 complex functions as an inhibitor of the amino acid-sensing branch of the TORC1 pathway. The GATOR1 complex strongly increases GTP hydrolysis by RRAGA and RRAGB within RRAGC-containing heterodimers, thereby deactivating RRAGs, releasing mTORC1 from lysosomal surface and inhibiting mTORC1 signaling. The GATOR1 complex is negatively regulated by GATOR2 the other GATOR subcomplex in this amino acid-sensing branch of the TORC1 pathway.,NPRL2,FFEVF2,NPR2,NPR2L,TUSC4,NPR2-like,Epigenetics & Nuclear Signaling,Cancer,Tumor suppressors,Cell Biology & Developmental Biology,Apoptosis,NPRL2
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                                            分子量
- 23 kDa/43 kDa
- 
                                            基因ID
- 10641
- 
                                            UniProt
- Q8WTW4
 抗原
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