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Merlin 抗体 (AA 477-576)

This anti-Merlin antibody is a 兔 多克隆 antibody detecting Merlin in WB, IF 和 IP. Suitable for 人.
产品编号 ABIN6144548
发货至: 中国

Quick Overview for Merlin 抗体 (AA 477-576) (ABIN6144548)

抗原

See all Merlin (NF2) 抗体
Merlin (NF2) (Neurofibromin 2 (NF2))

适用

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宿主

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克隆类型

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多克隆

标记

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This Merlin antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP)
  • 抗原表位

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    AA 477-576

    序列

    TKPTYPPMNP IPAPLPPDIP SFNLIGDSLS FDFKDTDMKR LSMEIEKEKV EYMEKSKHLQ EQLNELKTEI EALKLKERET ALDILHNENS DRGGSSKHNT

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 477-576 of human NF2 (NP_000259.1).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IF,1:50 - 1:200,IP,1:50 - 1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    Merlin (NF2) (Neurofibromin 2 (NF2))

    别名

    NF2

    背景

    This gene encodes a protein that is similar to some members of the ERM (ezrin, radixin, moesin) family of proteins that are thought to link cytoskeletal components with proteins in the cell membrane. This gene product has been shown to interact with cell-surface proteins, proteins involved in cytoskeletal dynamics and proteins involved in regulating ion transport. This gene is expressed at high levels during embryonic development, in adults, significant expression is found in Schwann cells, meningeal cells, lens and nerve. Mutations in this gene are associated with neurofibromatosis type II which is characterized by nervous system and skin tumors and ocular abnormalities. Two predominant isoforms and a number of minor isoforms are produced by alternatively spliced transcripts.,NF2,ACN,BANF,SCH,merlin,Epigenetics & Nuclear Signaling,Cancer,Tumor suppressors,Signal Transduction,Cell Biology & Developmental Biology,Cell Adhesion,Hippo Signaling Pathway,Neuroscience,NF2

    分子量

    19-30 kDa/59-72 kDa

    基因ID

    4771

    UniProt

    P35240

    途径

    Cell-Cell Junction Organization
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