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CD1d 抗体

This anti-CD1d antibody is a 小鼠 单克隆 antibody detecting CD1d in FACS, IHC (p) 和 IHC (fro). Suitable for 人.
产品编号 ABIN614443
发货至: 中国

Quick Overview for CD1d 抗体 (ABIN614443)

抗原

See all CD1d (CD1D) 抗体
CD1d (CD1D) (CD1d Molecule (CD1D))

适用

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宿主

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小鼠

克隆类型

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  • 1
单克隆

标记

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This CD1d antibody is un-conjugated

应用范围

  • 54
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Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

克隆位点

51-1
  • 特异性

    The monoclonal antibody reacts with Human CD1d.

    交叉反应 (详细)

    Species reactivity (tested):Human.

    纯化方法

    Affinity Chromatography

    免疫原

    Human CD1d

    亚型

    IgG2b
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    PBS, pH 7.2 containing < / = 0.09 % Sodium Azide as preservative

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C
  • 抗原

    CD1d (CD1D) (CD1d Molecule (CD1D))

    别名

    CD1d

    背景

    Human CD1d, a member of the CD1 family with similarity to the non-polymorphic MHC Class I-like molecules. CD1d is a highly conserved single transmembrane receptor of the Immunoglobulin Superfamily. CD1d can associate with beta-microglobulin another feature showing similarity to MHC class I molecules, but can also exist as a nonglycosylated protein not in association with beta microglobulin. This suggests different control mechanisms for presenting glycolipid containing molecules to CD1d reactive NKT cells. Expression of CD1d is found on B cells of the periphery, in resting monocytes and cortical thymocytes. On intestinal epithelial cells (IEC) expression is polarized. Expression can also be found at low levels intracellularly in hepatocytes. In HCV (hepatitis C virus) livers, CD1d is highly expressed compared to normal controls.Synonyms: R3G1, T-cell surface glycoprotein CD1d

    基因ID

    912

    NCBI登录号

    NP_001757

    UniProt

    P15813

    途径

    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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