MYH7 抗体 (AA 1766-1935)
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北京 101111
Quick Overview for MYH7 抗体 (AA 1766-1935) (ABIN6144239)
抗原
See all MYH7 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1766-1935
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序列
- AEELKKEQDT SAHLERMKKN MEQTIKDLQH RLDEAEQIAL KGGKKQLQKL EARVRELENE LEAEQKRNAE SVKGMRKSER RIKELTYQTE EDRKNLLRLQ DLVDKLQLKV KAYKRQAEEA EEQANTNLSK FRKVQHELDE AEERADIAES QVNKLRAKSR DIGTKGLNEE
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交叉反应
- 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 1766-1935 of human MYH7/beta-MHC (NP_000248.2).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:50 - 1:200
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说明
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HIGH QUALITY
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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: "Hypoxia-Induced Mitogenic Factor Promotes Cardiac Hypertrophy via Calcium-Dependent and Hypoxia-Inducible Factor-1α Mechanisms." in: Hypertension (Dallas, Tex. : 1979), Vol. 72, Issue 2, pp. 331-342, (2018) (PubMed).
: "Dietary leucine supplementation alters energy metabolism and induces slow-to-fast transitions in longissimus dorsi muscle of weanling piglets." in: The British journal of nutrition, Vol. 117, Issue 9, pp. 1222-1234, (2017) (PubMed).
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: "Hypoxia-Induced Mitogenic Factor Promotes Cardiac Hypertrophy via Calcium-Dependent and Hypoxia-Inducible Factor-1α Mechanisms." in: Hypertension (Dallas, Tex. : 1979), Vol. 72, Issue 2, pp. 331-342, (2018) (PubMed).
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- MYH7 (Myosin Heavy Chain 7, Cardiac Muscle, beta (MYH7))
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别名
- MYH7
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背景
- Muscle myosin is a hexameric protein containing 2 heavy chain subunits, 2 alkali light chain subunits, and 2 regulatory light chain subunits. This gene encodes the beta (or slow) heavy chain subunit of cardiac myosin. It is expressed predominantly in normal human ventricle. It is also expressed in skeletal muscle tissues rich in slow-twitch type I muscle fibers. Changes in the relative abundance of this protein and the alpha (or fast) heavy subunit of cardiac myosin correlate with the contractile velocity of cardiac muscle. Its expression is also altered during thyroid hormone depletion and hemodynamic overloading. Mutations in this gene are associated with familial hypertrophic cardiomyopathy, myosin storage myopathy, dilated cardiomyopathy, and Laing early-onset distal myopathy.,MYH7,CMD1S,CMH1,MPD1,MYHCB,SPMD,SPMM,myosin-7,MYH7,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Motor Proteins,MYH7
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分子量
- 223 kDa
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基因ID
- 4625
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UniProt
- P12883
抗原
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