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MYH11 抗体 (AA 1680-1979)

This anti-MYH11 antibody is a 兔 多克隆 antibody detecting MYH11 in WB 和 IF. Suitable for 人.
产品编号 ABIN6144234
发货至: 中国

Quick Overview for MYH11 抗体 (AA 1680-1979) (ABIN6144234)

抗原

See all MYH11 抗体
MYH11 (Myosin Heavy Chain 11, Smooth Muscle (MYH11))

适用

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宿主

  • 49
  • 9

克隆类型

  • 34
  • 24
多克隆

标记

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This MYH11 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF)
  • 抗原表位

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    AA 1680-1979

    序列

    ATAKENEKKA KSLEADLMQL QEDLAAAERA RKQADLEKEE LAEELASSLS GRNALQDEKR RLEARIAQLE EELEEEQGNM EAMSDRVRKA TQQAEQLSNE LATERSTAQK NESARQQLER QNKELRSKLH EMEGAVKSKF KSTIAALEAK IAQLEEQVEQ EAREKQAATK SLKQKDKKLK EILLQVEDER KMAEQYKEQA EKGNARVKQL KRQLEEAEEE SQRINANRRK LQRELDEATE SNEAMGREVN ALKSKLRRGN ETSFVPSRRS GGRRVIENAD GSEEETDTRD ADFNGTKASE

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 1680-1979 of human SMMHC/SMMHC/MYH11 (NP_001035203.1).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IF,1:50 - 1:200

    说明

    HIGH QUALITY

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    MYH11 (Myosin Heavy Chain 11, Smooth Muscle (MYH11))

    别名

    MYH11

    背景

    The protein encoded by this gene is a smooth muscle myosin belonging to the myosin heavy chain family. The gene product is a subunit of a hexameric protein that consists of two heavy chain subunits and two pairs of non-identical light chain subunits. It functions as a major contractile protein, converting chemical energy into mechanical energy through the hydrolysis of ATP. The gene encoding a human ortholog of rat NUDE1 is transcribed from the reverse strand of this gene, and its 3' end overlaps with that of the latter. The pericentric inversion of chromosome 16 [inv(16)(p13q22)] produces a chimeric transcript that encodes a protein consisting of the first 165 residues from the N terminus of core-binding factor beta in a fusion with the C-terminal portion of the smooth muscle myosin heavy chain. This chromosomal rearrangement is associated with acute myeloid leukemia of the M4Eo subtype. Alternative splicing generates isoforms that are differentially expressed, with ratios changing during muscle cell maturation. Alternatively spliced transcript variants encoding different isoforms have been identified.,MYH11,AAT4,FAA4,SMHC,SMMHC,myosin-11,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Motor Proteins,Stem Cells,Cardiovascular,Cardiovascular Markers,Smooth Muscle Cells,Heart,Contractility,MYH11

    分子量

    223 kDa/224 kDa/227 kDa/228 kDa

    基因ID

    4629

    UniProt

    P35749
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