MYBPC3 抗体 (AA 200-400)
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北京 101111
Quick Overview for MYBPC3 抗体 (AA 200-400) (ABIN6144221)
抗原
See all MYBPC3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 200-400
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序列
- SSKVGQHLQL HDSYDRASKV YLFELHITDA QPAFTGSYRC EVSTKDKFDC SNFNLTVHEA MGTGDLDLLS AFRRTSLAGG GRRISDSHED TGILDFSSLL KKRDSFRTPR DSKLEAPAEE DVWEILRQAP PSEYERIAFQ YGVTDLRGML KRLKGMRRDE KKSTAFQKKL EPAYQVSKGH KIRLTVELAD HDAEVKWLKN G
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交叉反应
- 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 200-400 of human MYBPC3 (NP_000247.2).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- MYBPC3 (Myosin Binding Protein C, Cardiac (MYBPC3))
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别名
- MYBPC3
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背景
- MYBPC3 encodes the cardiac isoform of myosin-binding protein C. Myosin-binding protein C is a myosin-associated protein found in the cross-bridge-bearing zone (C region) of A bands in striated muscle. MYBPC3, the cardiac isoform, is expressed exclussively in heart muscle. Regulatory phosphorylation of the cardiac isoform in vivo by cAMP-dependent protein kinase (PKA) upon adrenergic stimulation may be linked to modulation of cardiac contraction. Mutations in MYBPC3 are one cause of familial hypertrophic cardiomyopathy.,MYBPC3,CMD1MM,CMH4,FHC,LVNC10,MYBP-C,cardiac,Cell Biology & Developmental Biology,Cytoskeleton,Actins,Cardiovascular,Heart,Contractility,Hypertrophy,MYBPC3
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分子量
- 140 kDa
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基因ID
- 4607
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UniProt
- Q14896
抗原
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