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MXI1 抗体 (AA 76-295)

This anti-MXI1 antibody is a 兔 多克隆 antibody detecting MXI1 in WB. Suitable for 人.
产品编号 ABIN6144207
发货至: 中国

Quick Overview for MXI1 抗体 (AA 76-295) (ABIN6144207)

抗原

See all MXI1 抗体
MXI1 (MAX Interactor 1 (MXI1))

适用

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宿主

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克隆类型

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多克隆

标记

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This MXI1 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    AA 76-295

    序列

    LLEAASYLEQ IEKENKKCEH GYASSFPSMP SPRLQHSKPP RRLSRAQKHS SGSSNTSTAN RSTHNELEKN RRAHLRLCLE RLKVLIPLGP DCTRHTTLGL LNKAKAHIKK LEEAERKSQH QLENLEREQR FLKWRLEQLQ GPQEMERIRM DSIGSTISSD RSDSEREEIE VDVESTEFSH GEVDNISTTS ISDIDDHSSL PSIGSDEGYS SASVKLSFTS

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 76-295 of human MXI1 (NP_569157.2).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    MXI1 (MAX Interactor 1 (MXI1))

    别名

    MXI1

    背景

    Expression of the c-myc gene, which produces an oncogenic transcription factor, is tightly regulated in normal cells but is frequently deregulated in human cancers. The protein encoded by this gene is a transcriptional repressor thought to negatively regulate MYC function, and is therefore a potential tumor suppressor. This protein inhibits the transcriptional activity of MYC by competing for MAX, another basic helix-loop-helix protein that binds to MYC and is required for its function. Defects in this gene are frequently found in patients with prostate tumors. Three alternatively spliced transcripts encoding different isoforms have been described. Additional alternatively spliced transcripts may exist but the products of these transcripts have not been verified experimentally.,MXI1,MAD2,MXD2,MXI,bHLHc11,Epigenetics & Nuclear Signaling,Transcription Factors,MXI1

    分子量

    20 kDa/21 kDa/26 kDa/32 kDa

    基因ID

    4601

    UniProt

    P50539

    途径

    Maintenance of Protein Location
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