MXI1 抗体 (AA 76-295)
Quick Overview for MXI1 抗体 (AA 76-295) (ABIN6144207)
抗原
See all MXI1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 76-295
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序列
- LLEAASYLEQ IEKENKKCEH GYASSFPSMP SPRLQHSKPP RRLSRAQKHS SGSSNTSTAN RSTHNELEKN RRAHLRLCLE RLKVLIPLGP DCTRHTTLGL LNKAKAHIKK LEEAERKSQH QLENLEREQR FLKWRLEQLQ GPQEMERIRM DSIGSTISSD RSDSEREEIE VDVESTEFSH GEVDNISTTS ISDIDDHSSL PSIGSDEGYS SASVKLSFTS
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 76-295 of human MXI1 (NP_569157.2).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- MXI1 (MAX Interactor 1 (MXI1))
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别名
- MXI1
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背景
- Expression of the c-myc gene, which produces an oncogenic transcription factor, is tightly regulated in normal cells but is frequently deregulated in human cancers. The protein encoded by this gene is a transcriptional repressor thought to negatively regulate MYC function, and is therefore a potential tumor suppressor. This protein inhibits the transcriptional activity of MYC by competing for MAX, another basic helix-loop-helix protein that binds to MYC and is required for its function. Defects in this gene are frequently found in patients with prostate tumors. Three alternatively spliced transcripts encoding different isoforms have been described. Additional alternatively spliced transcripts may exist but the products of these transcripts have not been verified experimentally.,MXI1,MAD2,MXD2,MXI,bHLHc11,Epigenetics & Nuclear Signaling,Transcription Factors,MXI1
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分子量
- 20 kDa/21 kDa/26 kDa/32 kDa
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基因ID
- 4601
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UniProt
- P50539
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途径
- Maintenance of Protein Location
抗原
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