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MTF2 抗体 (AA 1-190)

This anti-MTF2 antibody is a 兔 多克隆 antibody detecting MTF2 in WB. Suitable for 人.
产品编号 ABIN6144136
发货至: 中国

Quick Overview for MTF2 抗体 (AA 1-190) (ABIN6144136)

抗原

See all MTF2 抗体
MTF2 (Metal Response Element Binding Transcription Factor 2 (MTF2))

适用

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宿主

  • 29
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克隆类型

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多克隆

标记

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This MTF2 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    AA 1-190

    序列

    MRDSTGAGNS LVHKRSPLRR NQKTPTSLTK LSLQDGHKAK KPACKFEEGQ DVLARWSDGL FYLGTIKKIN ILKQSCFIIF EDSSKSWVLW KDIQTGATGS GEMVCTICQE EYSEAPNEMV ICDKCGQGYH QLCHTPHIDS SVIDSDEKWL CRQCVFATTT KRGGALKKGP NAKALQVMKQ TLPYSVADLE

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 1-190 of human MTF2 (NP_001157864.1).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000

    说明

    HIGH QUALITY

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    MTF2 (Metal Response Element Binding Transcription Factor 2 (MTF2))

    别名

    MTF2

    背景

    Polycomb group (PcG protein that specifically binds histone H3 trimethylated at 'Lys-36' (H3K36me3 and recruits the PRC2 complex, thus enhancing PRC2 H3K27me3 methylation activity. Regulates the transcriptional networks during embryonic stem cell self-renewal and differentiation (By similarity. Promotes recruitment of the PRC2 complex to the inactive X chromosome in differentiating XX ES cells and PRC2 recruitment to target genes in undifferentiated ES cells (By similarity. Required to repress Hox genes by enhancing H3K27me3 methylation of the PRC2 complex (By similarity. In some conditions may act as an inhibitor of PRC2 activity: able to activate the CDKN2A gene and promote cellular senescence by suppressing the catalytic activity of the PRC2 complex locally (By similarity. Binds to the metal-regulating-element (MRE of MT1A gene promoter (By similarity.,MTF2,M96,PCL2,TDRD19A,dJ976O13.2,Epigenetics & Nuclear Signaling,Transcription Factors,Chromatin Remodeling,MTF2

    分子量

    29 kDa/55 kDa/60 kDa/67 kDa

    基因ID

    22823

    UniProt

    Q9Y483

    途径

    Stem Cell Maintenance
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