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MSL2 抗体 (AA 328-577)

This anti-MSL2 antibody is a 兔 多克隆 antibody detecting MSL2 in WB. Suitable for 人.
产品编号 ABIN6144069
发货至: 中国

Quick Overview for MSL2 抗体 (AA 328-577) (ABIN6144069)

抗原

See all MSL2 抗体
MSL2 (Male-Specific Lethal 2 Homolog (MSL2))

适用

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宿主

  • 22
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克隆类型

  • 22
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多克隆

标记

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This MSL2 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

    • 8
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    AA 328-577

    序列

    CTAATPKIAK LNRKRSRSES DSEKVQPLPI STIIRGPTLG ASAPVTVKRE SKISLQPIAT VPNGGTTPKI SKTVLLSTKS MKKSHEHGSK KSHSKTKPGI LKKDKAVKEK IPSHHFMPGS PTKTVYKKPQ EKKGCKCGRA TQNPSVLTCR GQRCPCYSNR KACLDCICRG CQNSYMANGE KKLEAFAVPE KALEQTRLTL GINVTSIAVR NASTSTSVIN VTGSPVTTFL AASTHDDKSL DEAIDMRFDC

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 328-577 of human MSL2 (NP_060603.2).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    MSL2 (Male-Specific Lethal 2 Homolog (MSL2))

    别名

    MSL2

    背景

    Component of histone acetyltransferase complex responsible for the majority of histone H4 acetylation at lysine 16 which is implicated in the formation of higher-order chromatin structure. Acts as an E3 ubiquitin ligase that promotes monoubiquitination of histone H2B at 'Lys-35' (H2BK34Ub, but not that of H2A. This activity is greatly enhanced by heterodimerization with MSL1. H2B ubiquitination in turn stimulates histone H3 methylation at 'Lys-4' (H3K4me and 'Lys-79' (H3K79me and leads to gene activation, including that of HOXA9 and MEIS1.,MSL2,MSL-2,MSL2L1,RNF184,Epigenetics & Nuclear Signaling,MSL2

    分子量

    54 kDa/62 kDa

    基因ID

    55167

    UniProt

    Q9HCI7
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