MSL2 抗体 (AA 328-577)
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- 抗原 See all MSL2 抗体
- MSL2 (Male-Specific Lethal 2 Homolog (MSL2))
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抗原表位
- AA 328-577
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MSL2 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- CTAATPKIAK LNRKRSRSES DSEKVQPLPI STIIRGPTLG ASAPVTVKRE SKISLQPIAT VPNGGTTPKI SKTVLLSTKS MKKSHEHGSK KSHSKTKPGI LKKDKAVKEK IPSHHFMPGS PTKTVYKKPQ EKKGCKCGRA TQNPSVLTCR GQRCPCYSNR KACLDCICRG CQNSYMANGE KKLEAFAVPE KALEQTRLTL GINVTSIAVR NASTSTSVIN VTGSPVTTFL AASTHDDKSL DEAIDMRFDC
- 交叉反应
- 人, 小鼠, 大鼠
- 产品特性
- Polyclonal Antibodies
- 免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 328-577 of human MSL2 (NP_060603.2).
- 亚型
- IgG
- Top Product
- Discover our top product MSL2 Primary Antibody
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- 应用备注
- WB,1:500 - 1:2000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- MSL2 (Male-Specific Lethal 2 Homolog (MSL2))
- 别名
- MSL2 (MSL2 产品)
- 背景
- Component of histone acetyltransferase complex responsible for the majority of histone H4 acetylation at lysine 16 which is implicated in the formation of higher-order chromatin structure. Acts as an E3 ubiquitin ligase that promotes monoubiquitination of histone H2B at 'Lys-35' (H2BK34Ub, but not that of H2A. This activity is greatly enhanced by heterodimerization with MSL1. H2B ubiquitination in turn stimulates histone H3 methylation at 'Lys-4' (H3K4me and 'Lys-79' (H3K79me and leads to gene activation, including that of HOXA9 and MEIS1.,MSL2,MSL-2,MSL2L1,RNF184,Epigenetics & Nuclear Signaling,MSL2
- 分子量
- 54 kDa/62 kDa
- 基因ID
- 55167
- UniProt
- Q9HCI7
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