SMCR7L 抗体 (AA 40-280)
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北京 101111
Quick Overview for SMCR7L 抗体 (AA 40-280) (ABIN6143839)
抗原
See all SMCR7L 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 40-280
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序列
- GIATLAVKRM YDRAISAPTS PTRLSHSGKR SWEEPNWMGS PRLLNRDMKT GLSRSLQTLP TDSSTFDTDT FCPPRPKPVA RKGQVDLKKS RLRMSLQEKL LTYYRNRAAI PAGEQARAKQ AAVDICAELR SFLRAKLPDM PLRDMYLSGS LYDDLQVVTA DHIQLIVPLV LEQNLWSCIP GEDTIMNVPG FFLVRRENPE YFPRGSSYWD RCVVGGYLSP KTVADTFEKV VAGSINWPAI G
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交叉反应
- 人
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产品特性
- Polyclonal Antibodies
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 40-280 of human MIEF1 (NP_061881.2).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- SMCR7L (Smith-Magenis Syndrome Chromosome Region, Candidate 7-Like (SMCR7L))
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别名
- MIEF1
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背景
- Mitochondrial outer membrane protein which regulates mitochondrial fission. Promotes the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L to the mitochondrial surface independently of the mitochondrial fission FIS1 and MFF proteins. Regulates DNM1L GTPase activity and DNM1L oligomerization. Binds ADP and can also bind GDP, although with lower affinity. Does not bind CDP, UDP, ATP, AMP or GTP. Inhibits DNM1L GTPase activity in the absence of bound ADP. Requires ADP to stimulate DNM1L GTPase activity and the assembly of DNM1L into long, oligomeric tubules with a spiral pattern, as opposed to the ring-like DNM1L oligomers observed in the absence of bound ADP. Does not require ADP for its function in recruiting DNM1L.,MIEF1,HSU79252,MID51,SMCR7L,dJ1104E15.3,Cell Biology & Developmental Biology,MIEF1
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分子量
- 8 kDa/15 kDa/51 kDa
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基因ID
- 54471
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UniProt
- Q9NQG6
抗原
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