EFHA1 抗体 (AA 50-150)
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北京 101111
Quick Overview for EFHA1 抗体 (AA 50-150) (ABIN6143833)
抗原
See all EFHA1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 50-150
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序列
- AWHHSRVSVA ARDGSFTVSA QKNVEHGIIY IGKPSLRKQR FMQFSSLEHE GEYYMTPRDF LFSVMFEQME RKTSVKKLTK KDIEDTLSGI QTAGCGSTFF R
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 50-150 of human MICU2 (NP_689939.1).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- EFHA1 (EF-Hand Domain Family, Member A1 (EFHA1))
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别名
- MICU2
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背景
- Key regulator of mitochondrial calcium uniporter (MCU required to limit calcium uptake by MCU when cytoplasmic calcium is low. MICU1 and MICU2 form a disulfide-linked heterodimer that stimulate and inhibit MCU activity, depending on the concentration of calcium. MICU2 acts as a gatekeeper of MCU that senses calcium level via its EF-hand domains: prevents channel opening at resting calcium, avoiding energy dissipation and cell-death triggering.,MICU2,1110008L20Rik,EFHA1,Cell Biology & Developmental Biology,MICU2
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分子量
- 49 kDa
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基因ID
- 221154
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UniProt
- Q8IYU8
抗原
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