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METTL13 抗体 (AA 540-699)

This 兔 多克隆 antibody specifically detects METTL13 in WB. It exhibits reactivity toward 人.
产品编号 ABIN6143756
发货至: 中国
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Quick Overview for METTL13 抗体 (AA 540-699) (ABIN6143756)

抗原

METTL13 (Methyltransferase Like 13 (METTL13))

适用

  • 12
  • 7
  • 6
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1

宿主

  • 12

克隆类型

  • 12
多克隆

标记

  • 12
This METTL13 antibody is un-conjugated

应用范围

  • 12
  • 2
  • 2
  • 2
  • 1
Western Blotting (WB)
  • 抗原表位

    • 3
    • 2
    • 2
    • 2
    • 1
    AA 540-699

    序列

    SQSDRMKVHI ADGLDYIASL AGGGEARPCY DVIMFDVDSK DPTLGMSCPP PAFVEQSFLQ KVKSILTPEG VFILNLVCRD LGLKDSVLAG LKAVFPLLYV RRIEGEVNEI LFCQLHPEQK LATPELLETA QALERTLRKP GRGWDDTYVL SDMLKTVKIV

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 540-699 of human METTL13 (NP_057019.3).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000

    说明

    HIGH QUALITY

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    METTL13 (Methyltransferase Like 13 (METTL13))

    别名

    METTL13

    背景

    Dual methyltransferase that catalyzes methylation of elongation factor 1-alpha (EEF1A1 and EEF1A2 at two different positions, and is therefore involved in the regulation of mRNA translation. Via its C-terminus, methylates EEF1A1 and EEF1A2 at the N-terminal residue 'Gly-2'. Via its N-terminus dimethylates EEF1A1 and EEF1A2 at residue 'Lys-55'. Has no activity towards core histones H2A, H2B, H3 and H4. Negatively regulates cell proliferation at G1/S transition via transcriptional suppression of cell cycle regulatory genes such as CDK4 and CDK6.,METTL13,5630401D24Rik,CGI-01,KIAA0859,feat,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,METTL13

    分子量

    44 kDa/61 kDa/68 kDa/72 kDa/78 kDa

    基因ID

    51603

    UniProt

    Q8N6R0
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