METTL13 抗体 (AA 540-699)
Quick Overview for METTL13 抗体 (AA 540-699) (ABIN6143756)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 540-699
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序列
- SQSDRMKVHI ADGLDYIASL AGGGEARPCY DVIMFDVDSK DPTLGMSCPP PAFVEQSFLQ KVKSILTPEG VFILNLVCRD LGLKDSVLAG LKAVFPLLYV RRIEGEVNEI LFCQLHPEQK LATPELLETA QALERTLRKP GRGWDDTYVL SDMLKTVKIV
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 540-699 of human METTL13 (NP_057019.3).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000
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说明
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HIGH QUALITY
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- METTL13 (Methyltransferase Like 13 (METTL13))
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别名
- METTL13
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背景
- Dual methyltransferase that catalyzes methylation of elongation factor 1-alpha (EEF1A1 and EEF1A2 at two different positions, and is therefore involved in the regulation of mRNA translation. Via its C-terminus, methylates EEF1A1 and EEF1A2 at the N-terminal residue 'Gly-2'. Via its N-terminus dimethylates EEF1A1 and EEF1A2 at residue 'Lys-55'. Has no activity towards core histones H2A, H2B, H3 and H4. Negatively regulates cell proliferation at G1/S transition via transcriptional suppression of cell cycle regulatory genes such as CDK4 and CDK6.,METTL13,5630401D24Rik,CGI-01,KIAA0859,feat,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,METTL13
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分子量
- 44 kDa/61 kDa/68 kDa/72 kDa/78 kDa
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基因ID
- 51603
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UniProt
- Q8N6R0
抗原
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