TNNI1 抗体
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Quick Overview for TNNI1 抗体 (ABIN614371)
抗原
See all TNNI1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- Recognizes Troponin I Skeletal (TNNI). Less than 0.05 % cross-reactivity with Cardiac TNI
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交叉反应 (详细)
- Species reactivity (tested):Human.
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纯化方法
- Protein A Chromatography.
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免疫原
- Mouse Skeletal muscle Troponin I.
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亚型
- IgG2b
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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缓冲液
- PBS, pH 7.4 with 0.09 % Sodium Azide as preservative.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- DO NOT FREEZE!
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储存条件
- 4 °C
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储存方法
- Store the antibody undiluted at 2-8 °C.
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- TNNI1 (Slow Skeletal Troponin I (TNNI1))
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背景
- Troponin I is part of a heteromeric complex playing an important role in the regulation of skeletal and cardiac muscle contraction. It consists of three subunits, troponin I (TnI), troponin T (TnT) and troponin C (TnC). Each subunit is responsible for part of troponin complex function. TnI inhibits ATPase activity of acto myosin and TnT and TnI are present in cardiac muscles in different forms than in skeletal muscles. Only one tissue specific isoform of TnI is described for cardiac muscle tissue (cTnI) and this is expressed only in myocardium. This antibody reacts with subunit I of the troponin complex in human myocardium, where it is the only troponin I isotype present. It does not cross-react with troponin I of skeletal muscle cells.Synonyms: TNNI1
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基因ID
- 7135
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NCBI登录号
- NP_003272
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UniProt
- P19237
抗原
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