MCFD2 抗体 (AA 27-146)
Quick Overview for MCFD2 抗体 (AA 27-146) (ABIN6143636)
抗原
See all MCFD2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 27-146
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序列
- EEPAASFSQP GSMGLDKNTV HDQEHIMEHL EGVINKPEAE MSPQELQLHY FKMHDYDGNN LLDGLELSTA ITHVHKEEGS EQAPLMSEDE LINIIDGVLR DDDKNNDGYI DYAEFAKSLQ
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 27-146 of human MCFD2 (NP_644808.1).
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亚型
- IgG
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anti-Multiple Coagulation Factor Deficiency 2 (MCFD2) (AA 1-146) antibody
MCFD2 适用: 人 WB, ELISA, IHC (p), RNAi 宿主: 小鼠 Monoclonal 3A5-G4 unconjugated
anti-Multiple Coagulation Factor Deficiency 2 (MCFD2) antibodyMCFD2 适用: 人 WB 宿主: 小鼠 Monoclonal 5C6 unconjugated
anti-Multiple Coagulation Factor Deficiency 2 (MCFD2) (AA 1-146) antibodyMCFD2 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal X1 unconjugated
anti-Multiple Coagulation Factor Deficiency 2 (MCFD2) antibodyMCFD2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 165CT13-1-6 unconjugated
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应用备注
- WB,1:500 - 1:2000,IHC,1:100 - 1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- MCFD2 (Multiple Coagulation Factor Deficiency 2 (MCFD2))
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别名
- MCFD2
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背景
- This gene encodes a soluble luminal protein with two calmodulin-like EF-hand motifs at its C-terminus. This protein forms a complex with LMAN1 (lectin mannose binding protein 1, also known as ERGIC-53) that facilitates the transport of coagulation factors V (FV) and VIII (FVIII) from the endoplasmic reticulum to the Golgi apparatus via an endoplasmic reticulum Golgi intermediate compartment (ERGIC). Mutations in this gene cause combined deficiency of FV and FVIII (F5F8D), a rare autosomal recessive bleeding disorder characterized by mild to moderate bleeding and coordinate reduction in plasma FV and FVIII levels. This protein has also been shown to maintain stem cell potential in adult central nervous system and is a marker for testicular germ cell tumors. The 3' UTR of this gene contains a transposon-like human repeat element named 'THE 1'. A processed RNA pseudogene of this gene is on chromosome 6p22.1. Alternative splicing results in multiple transcript variants encoding distinct isoforms.,MCFD2,F5F8D,F5F8D2,LMAN1IP,SDNSF,Signal Transduction,MCFD2
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分子量
- 10 kDa/14 kDa/16 kDa
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基因ID
- 90411
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UniProt
- Q8NI22
抗原
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