MCAM 抗体 (AA 447-646)
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北京 101111
Quick Overview for MCAM 抗体 (AA 447-646) (ABIN6143621)
抗原
See all MCAM 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 447-646
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序列
- VLNLSCEASG HPRPTISWNV NGTASEQDQD PQRVLSTLNV LVTPELLETG VECTASNDLG KNTSILFLEL VNLTTLTPDS NTTTGLSTST ASPHTRANST STERKLPEPE SRGVVIVAVI VCILVLAVLG AVLYFLYKKG KLPCRRSGKQ EITLPPSRKS ELVVEVKSDK LPEEMGLLQG SSGDKRAPGD QGEKYIDLRH
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 447-646 of human CD146/CD146/MCAM (NP_006491.2).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- MCAM (Melanoma Cell Adhesion Molecule (MCAM))
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别名
- MCAM
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背景
- Plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development. Acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2/FAK1, and a transient increase in the intracellular calcium concentration.,MCAM,CD146,MUC18,Cancer,Invasion and Metastasis,Signal Transduction,Cell Biology & Developmental Biology,Cell Adhesion,Cell Adhesion Molecules,Cytoskeleton,Immunology & Inflammation,CD markers,Stem Cells,Endothelial Progenitors,MCAM
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分子量
- 57 kDa/71 kDa
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基因ID
- 4162
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UniProt
- P43121
抗原
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