MATK 抗体 (AA 352-466)
Quick Overview for MATK 抗体 (AA 352-466) (ABIN6143578)
抗原
See all MATK 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 352-466
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序列
- PEALKHGKFT SKSDVWSFGV LLWEVFSYGR APYPKMSLKE VSEAVEKGYR MEPPEGCPGP VHVLMSSCWE AEPARRPPFR KLAEKLAREL RSAGAPASVS GQDADGSTSP RSQEP
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 352-466 of human MATK (NP_647611.1).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:200
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说明
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HIGH QUALITY
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- MATK (Megakaryocyte-Associated tyrosine Kinase (MATK))
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别名
- MATK
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背景
- The protein encoded by this gene has amino acid sequence similarity to Csk tyrosine kinase and has the structural features of the CSK subfamily: SRC homology SH2 and SH3 domains, a catalytic domain, a unique N terminus, lack of myristylation signals, lack of a negative regulatory phosphorylation site, and lack of an autophosphorylation site. This protein is thought to play a significant role in the signal transduction of hematopoietic cells. It is able to phosphorylate and inactivate Src family kinases, and may play an inhibitory role in the control of T-cell proliferation. This protein might be involved in signaling in some cases of breast cancer. Three alternatively spliced transcript variants that encode different isoforms have been described for this gene.,MATK,CHK,CTK,HHYLTK,HYL,HYLTK,Lsk,Epigenetics & Nuclear Signaling,Cancer,Signal Transduction,Kinase,Cell Biology & Developmental Biology,Cell Cycle,MATK
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分子量
- 51 kDa/56 kDa
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基因ID
- 4145
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UniProt
- P42679
抗原
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