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MATK 抗体 (AA 352-466)

This anti-MATK antibody is a 兔 多克隆 antibody detecting MATK in WB 和 IHC. Suitable for 人.
产品编号 ABIN6143578
发货至: 中国

Quick Overview for MATK 抗体 (AA 352-466) (ABIN6143578)

抗原

See all MATK 抗体
MATK (Megakaryocyte-Associated tyrosine Kinase (MATK))

适用

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  • 15

宿主

  • 57
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克隆类型

  • 58
  • 3
多克隆

标记

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This MATK antibody is un-conjugated

应用范围

  • 53
  • 25
  • 25
  • 13
  • 13
  • 8
  • 5
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  • 3
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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

    • 15
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    AA 352-466

    序列

    PEALKHGKFT SKSDVWSFGV LLWEVFSYGR APYPKMSLKE VSEAVEKGYR MEPPEGCPGP VHVLMSSCWE AEPARRPPFR KLAEKLAREL RSAGAPASVS GQDADGSTSP RSQEP

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 352-466 of human MATK (NP_647611.1).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IHC,1:50 - 1:200

    说明

    HIGH QUALITY

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    MATK (Megakaryocyte-Associated tyrosine Kinase (MATK))

    别名

    MATK

    背景

    The protein encoded by this gene has amino acid sequence similarity to Csk tyrosine kinase and has the structural features of the CSK subfamily: SRC homology SH2 and SH3 domains, a catalytic domain, a unique N terminus, lack of myristylation signals, lack of a negative regulatory phosphorylation site, and lack of an autophosphorylation site. This protein is thought to play a significant role in the signal transduction of hematopoietic cells. It is able to phosphorylate and inactivate Src family kinases, and may play an inhibitory role in the control of T-cell proliferation. This protein might be involved in signaling in some cases of breast cancer. Three alternatively spliced transcript variants that encode different isoforms have been described for this gene.,MATK,CHK,CTK,HHYLTK,HYL,HYLTK,Lsk,Epigenetics & Nuclear Signaling,Cancer,Signal Transduction,Kinase,Cell Biology & Developmental Biology,Cell Cycle,MATK

    分子量

    51 kDa/56 kDa

    基因ID

    4145

    UniProt

    P42679
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