LY6E 抗体 (AA 21-101)
Quick Overview for LY6E 抗体 (AA 21-101) (ABIN6143391)
抗原
See all LY6E 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 21-101
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序列
- LMCFSCLNQK SNLYCLKPTI CSDQDNYCVT VSASAGIGNL VTFGHSLSKT CSPACPIPEG VNVGVASMGI SCCQSFLCNF S
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交叉反应
- 人, 小鼠
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产品特性
- Polyclonal Antibodies
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 21-101 of human LY6E (NP_002337.1).
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亚型
- IgG
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应用备注
- WB,1:1000 - 1:2000,IF,1:50 - 1:200
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说明
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HIGH QUALITY
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- LY6E (Lymphocyte Antigen 6 Complex, Locus E (LY6E))
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别名
- LY6E
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背景
- GPI-anchored cell surface protein that regulates T-lymphocytes proliferation, differentiation, and activation. Regulates the T-cell receptor (TCR signaling by interacting with component CD3Z/CD247 at the plasma membrane, leading to CD3Z/CD247 phosphorylation modulation (By similarity. Restricts the entry of human coronaviruses, including SARS-CoV, MERS-CoV and SARS-CoV-2, by interfering with spike protein-mediated membrane fusion. Plays also an essential role in placenta formation by acting as the main receptor for syncytin-A (SynA. Therefore, participates in the normal fusion of syncytiotrophoblast layer I (SynT-I and in the proper morphogenesis of both fetal and maternal vasculatures within the placenta. May also act as a modulator of nicotinic acetylcholine receptors (nAChRs activity (By similarity.,LY6E,RIG-E,RIGE,SCA-2,SCA2,TSA-1,LY6E
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分子量
- 13 kDa
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基因ID
- 4061
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UniProt
- Q16553
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途径
- Hormone Transport
抗原
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