Lipin 1 抗体 (AA 741-890)
Quick Overview for Lipin 1 抗体 (AA 741-890) (ABIN6143300)
抗原
See all Lipin 1 (LPIN1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 741-890
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序列
- NERGTVLPQG PLLLSPSSLF SALHREVIEK KPEKFKVQCL TDIKNLFFPN TEPFYAAFGN RPADVYSYKQ VGVSLNRIFT VNPKGELVQE HAKTNISSYV RLCEVVDHVF PLLKRSHSSD FPCSDTFSNF TFWREPLPPF ENQDIHSASA
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交叉反应
- 大鼠
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产品特性
- Polyclonal Antibodies
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 741-890 of human Lipin 1 (NP_663731.1).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- Lipin 1 (LPIN1)
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别名
- LPIN1
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背景
- This gene encodes a magnesium-ion-dependent phosphatidic acid phosphohydrolase enzyme that catalyzes the penultimate step in triglyceride synthesis including the dephosphorylation of phosphatidic acid to yield diacylglycerol. Expression of this gene is required for adipocyte differentiation and it also functions as a nuclear transcriptional coactivator with some peroxisome proliferator-activated receptors to modulate expression of other genes involved in lipid metabolism. Mutations in this gene are associated with metabolic syndrome, type 2 diabetes, and autosomal recessive acute recurrent myoglobinuria (ARARM). This gene is also a candidate for several human lipodystrophy syndromes. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their full-length structures have not been determined.,LPIN1,PAP1,lipin 1,Signal Transduction,Cell Biology & Developmental Biology,Cell Cycle,Cell differentiation,Endocrine & Metabolism,Lipid Metabolism,Cholesterol Metabolism,Endocrine and metabolic diseases,Diabetes,Cardiovascular,Heart,Lipids,Cardiovascular diseases,Heart disease,LPIN1
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分子量
- 50 kDa/98 kDa/99-107 kDa
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基因ID
- 23175
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UniProt
- Q14693
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途径
- Monocarboxylic Acid Catabolic Process
抗原
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