LAT 抗体 (AA 28-233)
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Quick Overview for LAT 抗体 (AA 28-233) (ABIN6143099)
抗原
See all LAT 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 28-233
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序列
- HCHRLPGSYD STSSDSLYPR GIQFKRPHTV APWPPAYPPV TSYPPLSQPD LLPIPRSPQP LGGSHRTPSS RRDSDGANSV ASYENEEPAC EDADEDEDDY HNPGYLVVLP DSTPATSTAA PSAPALSTPG IRDSAFSMES IDDYVNVPES GESAEASLDG SREYVNVSQE LHPGAAKTEP AALSSQEAEE VEEEGAPDYE NLQELN
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交叉反应
- 人
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产品特性
- Polyclonal Antibodies
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 28-233 of human LAT (NP_001014987.1).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- LAT (Linker For Activation of T Cells (LAT))
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别名
- LAT
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背景
- The protein encoded by this gene is phosphorylated by ZAP-70/Syk protein tyrosine kinases following activation of the T-cell antigen receptor (TCR) signal transduction pathway. This transmembrane protein localizes to lipid rafts and acts as a docking site for SH2 domain-containing proteins. Upon phosphorylation, this protein recruits multiple adaptor proteins and downstream signaling molecules into multimolecular signaling complexes located near the site of TCR engagement. Alternative splicing results in multiple transcript variants encoding different isoforms.,LAT,LAT1,pp36,IMD52,Signal Transduction,G protein signaling,Signal Transduction,Immunology & Inflammation,T Cell Receptor Signaling Pathway,LAT
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分子量
- 24 kDa/27 kDa/28 kDa
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基因ID
- 27040
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UniProt
- O43561
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途径
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway
抗原
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