CBR1 抗体
Our Local Distributor
北京 101111
Quick Overview for CBR1 抗体 (ABIN614308)
抗原
See all CBR1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
特异性
- The antibody recognizes human CBR1. Other species not tested.
-
纯化方法
- Protein-G affinity chromatography
-
亚型
- IgG2a
-
-
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1.0 mg/mL
-
缓冲液
- PBS, pH 7.4, containing 0.09 % sodium azide
-
储存液
- Sodium azide
-
注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
-
- CBR1 (Carbonyl Reductase 1 (CBR1))
-
别名
- Carbonyl Reductase 1
-
背景
- Carbonyl reductase 1 (CBR1) is a NADPH-dependent, monomeric, and cytosolic enzyme belonging to a family of short-chain dehydrogenases/reductases. This protein consists of 277 amino acid residues and is widely distributed in human tissues such as liver, epidermis, stomach, small intestine, kidney, neuronal cells, and smooth muscle fiber. CBR1 metabolizes many toxic environmental quinones and pharmacological relevant substrates such as the anticancer drug, doxorubicin. The best substrates of CBR1 are quinones, including ubiquinone-1 and tocophrolquinone (vitamin E).Synonyms: 15-hydroxyprostaglandin dehydrogenase [NADP+], CBR, CBR1, CRN, NADPH-dependent carbonyl reductase 1, Prostaglandin 9-ketoreductase, Prostaglandin-E(2) 9-reductase
-
基因ID
- 873
抗原
-