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LAMC2 抗体 (AA 862-1111)

LAMC2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6143076
发货至: 中国
  • 抗原 See all LAMC2 抗体
    LAMC2 (Laminin, gamma 2 (LAMC2))
    抗原表位
    • 8
    • 7
    • 6
    • 6
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 862-1111
    适用
    • 28
    • 24
    • 8
    • 1
    • 1
    • 1
    宿主
    • 45
    • 3
    克隆类型
    • 46
    • 2
    多克隆
    标记
    • 23
    • 6
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This LAMC2 antibody is un-conjugated
    应用范围
    • 37
    • 22
    • 12
    • 6
    • 4
    • 4
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    序列
    SDQSFQVEEA KRIKQKADSL SSLVTRHMDE FKRTQKNLGN WKEEAQQLLQ NGKSGREKSD QLLSRANLAK SRAQEALSMG NATFYEVESI LKNLREFDLQ VDNRKAEAEE AMKRLSYISQ KVSDASDKTQ QAERALGSAA ADAQRAKNGA GEALEISSEI EQEIGSLNLE ANVTADGALA MEKGLASLKS EMREVEGELE RKELEFDTNM DAVQMVITEA QKVDTRAKNA GVTIQDTLNT LDGLLHLMGM
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Polyclonal Antibodies
    免疫原
    Recombinant fusion protein containing a sequence corresponding to amino acids 862-1111 of human LAMC2 (NP_061486.2).
    亚型
    IgG
    Top Product
    Discover our top product LAMC2 Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000,IF,1:50 - 1:100
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    LAMC2 (Laminin, gamma 2 (LAMC2))
    别名
    LAMC2 (LAMC2 产品)
    别名
    LAMC2 antibody, B2T antibody, BM600 antibody, CSF antibody, EBR2 antibody, EBR2A antibody, LAMB2T antibody, LAMNB2 antibody, AA589349 antibody, laminin subunit gamma 2 antibody, laminin, gamma 2 antibody, LAMC2 antibody, Lamc2 antibody
    背景
    This gene encodes the gamma chain isoform laminin, gamma 2. The gamma 2 chain, formerly thought to be a truncated version of beta chain (B2t), is highly homologous to the gamma 1 chain, however, it lacks domain VI, and domains V, IV and III are shorter. It is expressed in several fetal tissues but differently from gamma 1, and is specifically localized to epithelial cells in skin, lung and kidney. The gamma 2 chain together with alpha 3 and beta 3 chains constitute laminin 5 (earlier known as kalinin), which is an integral part of the anchoring filaments that connect epithelial cells to the underlying basement membrane. The epithelium-specific expression of the gamma 2 chain implied its role as an epithelium attachment molecule, and mutations in this gene have been associated with junctional epidermolysis bullosa, a skin disease characterized by blisters due to disruption of the epidermal-dermal junction. Two transcript variants resulting from alternative splicing of the 3' terminal exon, and encoding different isoforms of gamma 2 chain, have been described. The two variants are differentially expressed in embryonic tissues, however, the biological significance of the two forms is not known. Transcript variants utilizing alternative polyA_signal have also been noted in literature.,LAMC2,B2T,BM600,CSF,EBR2,EBR2A,LAMB2T,LAMNB2,Signal Transduction,Cell Biology & Developmental Biology,Cell Adhesion,Cytoskeleton,Neuroscience,LAMC2
    分子量
    121 kDa/130 kDa
    基因ID
    3918
    UniProt
    Q13753
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