LAMC2 抗体 (AA 862-1111)
Quick Overview for LAMC2 抗体 (AA 862-1111) (ABIN6143076)
抗原
See all LAMC2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 862-1111
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序列
- SDQSFQVEEA KRIKQKADSL SSLVTRHMDE FKRTQKNLGN WKEEAQQLLQ NGKSGREKSD QLLSRANLAK SRAQEALSMG NATFYEVESI LKNLREFDLQ VDNRKAEAEE AMKRLSYISQ KVSDASDKTQ QAERALGSAA ADAQRAKNGA GEALEISSEI EQEIGSLNLE ANVTADGALA MEKGLASLKS EMREVEGELE RKELEFDTNM DAVQMVITEA QKVDTRAKNA GVTIQDTLNT LDGLLHLMGM
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 862-1111 of human LAMC2 (NP_061486.2).
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亚型
- IgG
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anti-Laminin, gamma 2 (LAMC2) (AA 416-602) antibody
LAMC2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Laminin, gamma 2 (LAMC2) (AA 28-196) antibodyLAMC2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Laminin, gamma 2 (LAMC2) (C-Term) antibodyLAMC2 适用: 人, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Laminin, gamma 2 (LAMC2) (AA 417-588) antibodyLAMC2 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Laminin, gamma 2 (LAMC2) (AA 1084-1193) antibodyLAMC2 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Laminin, gamma 2 (LAMC2) antibodyLAMC2 适用: 人, 小鼠, 大鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-Laminin, gamma 2 (LAMC2) (AA 28-196) antibodyLAMC2 适用: 人 WB 宿主: 小鼠 Monoclonal D7 unconjugated
anti-Laminin, gamma 2 (LAMC2) antibodyLAMC2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Laminin, gamma 2 (LAMC2) (C-Term) antibodyLAMC2 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Laminin, gamma 2 (LAMC2) (C-Term) antibodyLAMC2 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB,1:500 - 1:2000,IF,1:50 - 1:100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- LAMC2 (Laminin, gamma 2 (LAMC2))
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别名
- LAMC2
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背景
- This gene encodes the gamma chain isoform laminin, gamma 2. The gamma 2 chain, formerly thought to be a truncated version of beta chain (B2t), is highly homologous to the gamma 1 chain, however, it lacks domain VI, and domains V, IV and III are shorter. It is expressed in several fetal tissues but differently from gamma 1, and is specifically localized to epithelial cells in skin, lung and kidney. The gamma 2 chain together with alpha 3 and beta 3 chains constitute laminin 5 (earlier known as kalinin), which is an integral part of the anchoring filaments that connect epithelial cells to the underlying basement membrane. The epithelium-specific expression of the gamma 2 chain implied its role as an epithelium attachment molecule, and mutations in this gene have been associated with junctional epidermolysis bullosa, a skin disease characterized by blisters due to disruption of the epidermal-dermal junction. Two transcript variants resulting from alternative splicing of the 3' terminal exon, and encoding different isoforms of gamma 2 chain, have been described. The two variants are differentially expressed in embryonic tissues, however, the biological significance of the two forms is not known. Transcript variants utilizing alternative polyA_signal have also been noted in literature.,LAMC2,B2T,BM600,CSF,EBR2,EBR2A,LAMB2T,LAMNB2,Signal Transduction,Cell Biology & Developmental Biology,Cell Adhesion,Cytoskeleton,Neuroscience,LAMC2
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分子量
- 121 kDa/130 kDa
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基因ID
- 3918
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UniProt
- Q13753
抗原
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