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L1CAM 抗体 (AA 1143-1257)

This anti-L1CAM antibody is a 兔 多克隆 antibody detecting L1CAM in WB 和 IF. Suitable for 人.
产品编号 ABIN6143053
发货至: 中国

Quick Overview for L1CAM 抗体 (AA 1143-1257) (ABIN6143053)

抗原

See all L1CAM 抗体
L1CAM (L1 Cell Adhesion Molecule (L1CAM))

适用

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宿主

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克隆类型

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多克隆

标记

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This L1CAM antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF)
  • 抗原表位

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    AA 1143-1257

    序列

    IKRSKGGKYS VKDKEDTQVD SEARPMKDET FGEYRSLESD NEEKAFGSSQ PSLNGDIKPL GSDDSLADYG GSVDVQFNED GSFIGQYSGK KEKEAAGGND SSGATSPINP AVALE

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 1143-1257 of human L1CAM (NP_000416.1).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IF,1:50 - 1:200

    说明

    HIGH QUALITY

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    L1CAM (L1 Cell Adhesion Molecule (L1CAM))

    别名

    L1CAM

    背景

    The protein encoded by this gene is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain, consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III), is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation. Mutations in the gene cause X-linked neurological syndromes known as CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic paraplegia and hydrocephalus). Alternative splicing of this gene results in multiple transcript variants, some of which include an alternate exon that is considered to be specific to neurons.,L1CAM,CAML1,CD171,HSAS,HSAS1,MASA,MIC5,N-CAM-L1,N-CAML1,NCAM-L1,S10,SPG1,Signal Transduction,Cell Biology & Developmental Biology,Cell Adhesion,Cell Adhesion Molecules,Cytoskeleton,Immunology & Inflammation,CD markers,Neuroscience,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,Neurodegenerative Diseases Markers,L1CAM

    分子量

    138 kDa/139 kDa/140 kDa

    基因ID

    3897

    UniProt

    P32004

    途径

    Synaptic Membrane
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