KHDRBS3 抗体 (AA 177-346)
Quick Overview for KHDRBS3 抗体 (AA 177-346) (ABIN6142833)
抗原
See all KHDRBS3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 177-346
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序列
- GSENADVPVV RGKPTLRTRG VPAPAITRGR GGVTARPVGV VVPRGTPTPR GVLSTRGPVS RGRGLLTPRA RGVPPTGYRP PPPPPTQETY GEYDYDDGYG TAYDEQSYDS YDNSYSTPAQ SGADYYDYGH GLSEETYDSY GQEEWTNSRH KAPSARTAKG VYRDQPYGRY
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交叉反应
- 人, 小鼠
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产品特性
- Polyclonal Antibodies
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 177-346 of human KHDRBS3 (NP_006549.1).
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亚型
- IgG
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anti-KH Domain Containing, RNA Binding, Signal Transduction Associated 3 (KHDRBS3) (AA 177-346) antibody
KHDRBS3 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-KH Domain Containing, RNA Binding, Signal Transduction Associated 3 (KHDRBS3) (AA 1-346) antibodyKHDRBS3 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-KH Domain Containing, RNA Binding, Signal Transduction Associated 3 (KHDRBS3) (C-Term) antibodyKHDRBS3 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-KH Domain Containing, RNA Binding, Signal Transduction Associated 3 (KHDRBS3) antibodyKHDRBS3 适用: 人, 小鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-KH Domain Containing, RNA Binding, Signal Transduction Associated 3 (KHDRBS3) (N-Term) antibodyKHDRBS3 适用: 人, Cow, 犬, 豚鼠, 马, 兔, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-KH Domain Containing, RNA Binding, Signal Transduction Associated 3 (KHDRBS3) (C-Term) antibodyKHDRBS3 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB,1:500 - 1:2000,IF,1:50 - 1:100
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说明
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HIGH QUALITY
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- KHDRBS3 (KH Domain Containing, RNA Binding, Signal Transduction Associated 3 (KHDRBS3))
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别名
- KHDRBS3
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背景
- RNA-binding protein that plays a role in the regulation of alternative splicing and influences mRNA splice site selection and exon inclusion. Binds preferentially to the 5'-[AU]UAAA-3' motif in vitro. Binds optimally to RNA containing 5'-[AU]UAA-3' as a bipartite motif spaced by more than 15 nucleotides. Binds poly(A. RNA-binding abilities are down-regulated by tyrosine kinase PTK6. Involved in splice site selection of vascular endothelial growth factor. In vitro regulates CD44 alternative splicing by direct binding to purine-rich exonic enhancer (By similarity. Can regulate alternative splicing of neurexins NRXN1-3 in the laminin G-like domain 6 containing the evolutionary conserved neurexin alternative spliced segment 4 (AS4 involved in neurexin selective targeting to postsynaptic partners such as neuroligins and LRRTM family members. Targeted, cell-type specific splicing regulation of NRXN1 at AS4 is involved in neuronal glutamatergic synapse function and plasticity (By similarity. May regulate expression of KHDRBS2/SLIM-1 in defined brain neuron populations by modifying its alternative splicing (By similarity. Can bind FABP9 mRNA (By similarity. May play a role as a negative regulator of cell growth. Inhibits cell proliferation.,KHDRBS3,Etle,SALP,SLM-2,SLM2,T-STAR,TSTAR,etoile,Epigenetics & Nuclear Signaling,KHDRBS3
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分子量
- 30 kDa/38 kDa
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基因ID
- 10656
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UniProt
- O75525
抗原
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