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ITGA8 抗体 (AA 907-1000)

This anti-ITGA8 antibody is a 兔 多克隆 antibody detecting ITGA8 in WB. Suitable for 人.
产品编号 ABIN6142568
发货至: 中国

Quick Overview for ITGA8 抗体 (AA 907-1000) (ABIN6142568)

抗原

See all ITGA8 抗体
ITGA8 (Integrin alpha-8 (ITGA8))

适用

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宿主

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克隆类型

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多克隆

标记

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This ITGA8 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    AA 907-1000

    序列

    DVHVVEFHRQ SPAKILNCTN IECLQISCAV GRLEGGESAV LKVRSRLWAH TFLQRKNDPY ALASLVSFEV KKMPYTDQPA KLPEGSIVIK TSVI

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 907-1000 of human ITGA8 (NP_003629.2).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000

    说明

    HIGH QUALITY

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    ITGA8 (Integrin alpha-8 (ITGA8))

    别名

    ITGA8

    背景

    Integrins are heterodimeric transmembrane receptor proteins that mediate numerous cellular processes including cell adhesion, cytoskeletal rearrangement, and activation of cell signaling pathways. Integrins are composed of alpha and beta subunits. This gene encodes the alpha 8 subunit of the heterodimeric integrin alpha8beta1 protein. The encoded protein is a single-pass type 1 membrane protein that contains multiple FG-GAP repeats. This repeat is predicted to fold into a beta propeller structure. This gene regulates the recruitment of mesenchymal cells into epithelial structures, mediates cell-cell interactions, and regulates neurite outgrowth of sensory and motor neurons. The integrin alpha8beta1 protein thus plays an important role in wound-healing and organogenesis. Mutations in this gene have been associated with renal hypodysplasia/aplasia-1 (RHDA1) and with several animal models of chronic kidney disease. Alternate splicing results in multiple transcript variants encoding distinct isoforms.,ITGA8,Signal Transduction,PI3K-Akt Signaling Pathway,MAPK-Erk Signaling Pathway,Cell Biology & Developmental Biology,Cell Adhesion,Cytoskeleton,ITGA8

    分子量

    117 kDa

    基因ID

    8516

    UniProt

    P53708
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