IRS2 抗体 (AA 510-650)
Quick Overview for IRS2 抗体 (AA 510-650) (ABIN6142544)
抗原
See all IRS2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 510-650
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序列
- LRAFCSHRSN TPESIAETPP ARDGGGGGEF YGYMTMDRPL SHCGRSYRRV SGDAAQDLDR GLRKRTYSLT TPARQRPVPQ PSSASLDEYT LMRATFSGSA GRLCPSCPAS SPKVAYHPYP EDYGDIEIGS HRSSSSNLGA D
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 510-650 of human IRS2 (NP_003740.2).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000,IF,1:50 - 1:200
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说明
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HIGH QUALITY
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- IRS2 (Insulin Receptor Substrate 2 (IRS2))
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别名
- IRS2
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背景
- This gene encodes the insulin receptor substrate 2, a cytoplasmic signaling molecule that mediates effects of insulin, insulin-like growth factor 1, and other cytokines by acting as a molecular adaptor between diverse receptor tyrosine kinases and downstream effectors. The product of this gene is phosphorylated by the insulin receptor tyrosine kinase upon receptor stimulation, as well as by an interleukin 4 receptor-associated kinase in response to IL4 treatment.,IRS2,IRS-2,Cancer,Signal Transduction,MAPK-Erk Signaling Pathway,Cell Biology & Developmental Biology,Growth factor,Endocrine & Metabolism,Insulin Receptor Signaling Pathway,Endocrine and metabolic diseases,Diabetes,Immunology & Inflammation,Cardiovascular,Heart,Cardiovascular diseases,Heart disease,IRS2
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分子量
- 137 kDa
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基因ID
- 8660
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UniProt
- Q9Y4H2
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途径
- Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Response to Growth Hormone Stimulus, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process
抗原
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