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ING3 抗体 (AA 1-92)

This anti-ING3 antibody is a 兔 多克隆 antibody detecting ING3 in WB. Suitable for 人.
产品编号 ABIN6142450
发货至: 中国

Quick Overview for ING3 抗体 (AA 1-92) (ABIN6142450)

抗原

See all ING3 抗体
ING3 (Inhibitor of Growth Family, Member 3 (ING3))

适用

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宿主

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克隆类型

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多克隆

标记

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This ING3 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    AA 1-92

    序列

    MLYLEDYLEM IEQLPMDLRD RFTEMREMDL QVQNAMDQLE QRVSEFFMNA KKNKPEWREE QMASIKKDYY KALEDADEKV QLANQIYDLQ HF

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 1-92 of human ING3 (NP_938008.1).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000

    说明

    HIGH QUALITY

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    ING3 (Inhibitor of Growth Family, Member 3 (ING3))

    别名

    ING3

    背景

    The protein encoded by this gene is similar to ING1, a tumor suppressor protein that can interact with TP53, inhibit cell growth, and induce apoptosis. This protein contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. This gene can activate p53 trans-activated promoters, including promoters of p21/waf1 and bax. Overexpression of this gene has been shown to inhibit cell growth and induce apoptosis. Allelic loss and reduced expression of this gene were detected in head and neck cancers. Two alternatively spliced transcript variants encoding different isoforms have been observed.,ING3,Eaf4,ING2,MEAF4,p47ING3,Epigenetics & Nuclear Signaling,Cancer,Tumor suppressors,ING3

    分子量

    11 kDa/46 kDa

    基因ID

    54556

    UniProt

    Q9NXR8
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