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IL17RA 抗体 (AA 697-866)

This anti-IL17RA antibody is a 兔 多克隆 antibody detecting IL17RA in WB. Suitable for 人. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN6142322
发货至: 中国

Quick Overview for IL17RA 抗体 (AA 697-866) (ABIN6142322)

抗原

See all IL17RA 抗体
IL17RA (Interleukin 17 Receptor A (IL17RA))

适用

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宿主

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克隆类型

  • 74
  • 19
多克隆

标记

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This IL17RA antibody is un-conjugated

应用范围

  • 71
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Western Blotting (WB)
  • 抗原表位

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    AA 697-866

    序列

    AGEGEACPLL GSPGAGRNSV LFLPVDPEDS PLGSSTPMAS PDLLPEDVRE HLEGLMLSLF EQSLSCQAQG GCSRPAMVLT DPHTPYEEEQ RQSVQSDQGY ISRSSPQPPE GLTEMEEEEE EEQDPGKPAL PLSPEDLESL RSLQRQLLFR QLQKNSGWDT MGSESEGPSA

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 697-866 of human IL17RA (NP_055154.3).

    亚型

    IgG
  • 应用备注

    WB,1:1000 - 1:4000

    说明

    HIGH QUALITY

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • Ganesan, Rasool: "Interleukin 17 regulates SHP-2 and IL-17RA/STAT-3 dependent Cyr61, IL-23 and GM-CSF expression and RANKL mediated osteoclastogenesis by fibroblast-like synoviocytes in rheumatoid arthritis." in: Molecular immunology, Vol. 91, pp. 134-144, (2017) (PubMed).

  • 抗原

    IL17RA (Interleukin 17 Receptor A (IL17RA))

    别名

    IL17RA

    背景

    Interleukin 17A (IL17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The transmembrane protein encoded by this gene (interleukin 17A receptor, IL17RA) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure. Alternative splicing results in multiple transcript variants encoding different isoforms.,IL17RA,CANDF5,CD217,CDw217,IL-17RA,IL17R,IMD51,hIL-17R,Immunology & Inflammation,CD markers,Cytokines,Interleukins,Cell Intrinsic Innate Immunity Signaling Pathway,IL17RA

    分子量

    92 kDa/96 kDa

    基因ID

    23765

    UniProt

    Q96F46

    途径

    SARS-CoV-2 Protein Interactome
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